Journal Article DKFZ-2025-01880

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Tumor Versus Capillary Telangiectasia in Recurring Glioblastoma.

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2025
Lippincott Williams & Wilkins Philadelphia, Pa.

Clinical nuclear medicine nn, nn () [10.1097/RLU.0000000000006125]
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Abstract: This image highlights a diagnostic pitfall in a 65-year-old patient with recurrent glioblastoma. 18F-FET-PET revealed 2 hotspots with focally enhanced uptake: local tumor recurrence (TBRmax 2.3) on the left and another lesion in the right anterior cingulate gyrus (TBRmax 1.8), suspicious for a distant tumor manifestation. However, multimodal MRI revealed a benign capillary telangiectasia in the anterior cingulate gyrus. While 18F-FET-PET is highly sensitive for detecting tumor activity, vascular malformations may also exhibit moderate tracer uptake. Therefore, careful interpretation and comparison with multiple MRI sequences are essential.

Keyword(s): FET-PET ; diagnostic pitfall ; glioblastoma

Classification:

Note: epub

Contributing Institute(s):
  1. DKTK Koordinierungsstelle München (MU01)
Research Program(s):
  1. 899 - ohne Topic (POF4-899) (POF4-899)

Appears in the scientific report 2025
Database coverage:
Medline ; Allianz-Lizenz ; Clarivate Analytics Master Journal List ; Current Contents - Clinical Medicine ; Essential Science Indicators ; IF >= 10 ; JCR ; SCOPUS ; Science Citation Index Expanded ; Web of Science Core Collection
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 Record created 2025-09-10, last modified 2025-09-14



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