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@ARTICLE{Lou:305422,
author = {F. Lou and C. Duan and Z. Quan and J. Qu and C. Guo and A.
M. Nagel$^*$ and X. Lou and X. Zhang},
title = {{A} {D}ouble-{L}ayer 1{H}/23{N}a {T}ransceiver {A}rray for
{H}uman {B}rain {MRI} at 7{T}.},
journal = {NMR in biomedicine},
volume = {38},
number = {12},
issn = {0952-3480},
address = {New York, NY},
publisher = {Wiley},
reportid = {DKFZ-2025-02151},
pages = {e70162},
year = {2025},
abstract = {With the increasing adoption of ultra-high-field (UHF)
systems, sodium (23Na) imaging is undergoing clinical
translation. However, existing commercially available
dual-tuned coils, while demonstrating adequate sodium
signal-to-noise ratio (SNR), fail to meet the requirements
for high-resolution proton (1H) structural imaging,
resulting in suboptimal workflow efficiency during
integrated multi-nucleus examinations. In this work, we
present a novel double-layer 1H/23Na transceiver array with
eight channels per nucleus for human brain MRI at 7T. The
proposed array achieved $64\%$ of the 1H SNR of the
32-channel receive array commonly used in clinical practice.
By integrating dual-nucleus imaging capabilities within a
single platform, this design eliminates coil-switching
requirements and post-acquisition registration, thereby
streamlining clinical workflows and advancing sodium MRI
translational feasibility.},
keywords = {Humans / Magnetic Resonance Imaging: instrumentation /
Brain: diagnostic imaging / Sodium / Signal-To-Noise Ratio /
Protons / Equipment Design / Sodium Isotopes / RF coil
(Other) / sodium MRI (Other) / ultra‐high‐field MRI
(Other) / Sodium (NLM Chemicals) / Protons (NLM Chemicals) /
Sodium Isotopes (NLM Chemicals)},
cin = {E020},
ddc = {610},
cid = {I:(DE-He78)E020-20160331},
pnm = {315 - Bildgebung und Radioonkologie (POF4-315)},
pid = {G:(DE-HGF)POF4-315},
typ = {PUB:(DE-HGF)16},
pubmed = {pmid:41098051},
doi = {10.1002/nbm.70162},
url = {https://inrepo02.dkfz.de/record/305422},
}