Journal Article DKFZ-2025-02151

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A Double-Layer 1H/23Na Transceiver Array for Human Brain MRI at 7T.

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2025
Wiley New York, NY

NMR in biomedicine 38(12), e70162 () [10.1002/nbm.70162]
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Abstract: With the increasing adoption of ultra-high-field (UHF) systems, sodium (23Na) imaging is undergoing clinical translation. However, existing commercially available dual-tuned coils, while demonstrating adequate sodium signal-to-noise ratio (SNR), fail to meet the requirements for high-resolution proton (1H) structural imaging, resulting in suboptimal workflow efficiency during integrated multi-nucleus examinations. In this work, we present a novel double-layer 1H/23Na transceiver array with eight channels per nucleus for human brain MRI at 7T. The proposed array achieved 64% of the 1H SNR of the 32-channel receive array commonly used in clinical practice. By integrating dual-nucleus imaging capabilities within a single platform, this design eliminates coil-switching requirements and post-acquisition registration, thereby streamlining clinical workflows and advancing sodium MRI translational feasibility.

Keyword(s): Humans (MeSH) ; Magnetic Resonance Imaging: instrumentation (MeSH) ; Brain: diagnostic imaging (MeSH) ; Sodium (MeSH) ; Signal-To-Noise Ratio (MeSH) ; Protons (MeSH) ; Equipment Design (MeSH) ; Sodium Isotopes (MeSH) ; RF coil ; sodium MRI ; ultra‐high‐field MRI ; Sodium ; Protons ; Sodium Isotopes

Classification:

Contributing Institute(s):
  1. E020 Med. Physik in der Radiologie (E020)
Research Program(s):
  1. 315 - Bildgebung und Radioonkologie (POF4-315) (POF4-315)

Appears in the scientific report 2025
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Medline ; Clarivate Analytics Master Journal List ; Current Contents - Life Sciences ; DEAL Wiley ; Essential Science Indicators ; IF < 5 ; JCR ; NationallizenzNationallizenz ; SCOPUS ; Science Citation Index Expanded ; Web of Science Core Collection
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 Record created 2025-10-17, last modified 2025-10-20



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