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@ARTICLE{Simmchen:305571,
      author       = {J. Simmchen and D. Gordon and J. MacKenzie and I.
                      Pagonabarraga and C. C. Roggatz and R. G. Endres and Z. Xiao
                      and B. M. Friedrich and T. Qiu$^*$ and K. J. Painter and R.
                      Golestanian and C. Contini and M. C. Ucar and G. Yossifon
                      and J. U. Sommer and W.-J. Rappel and K. Y. Wan and J.
                      Armitage and R. Insall},
      title        = {{P}erspective on {I}nterdisciplinary {A}pproaches on
                      {C}hemotaxis.},
      journal      = {Angewandte Chemie / International edition},
      volume       = {64},
      number       = {47},
      issn         = {1433-7851},
      address      = {Weinheim},
      publisher    = {Wiley-VCH},
      reportid     = {DKFZ-2025-02233},
      pages        = {e202504790},
      year         = {2025},
      note         = {2025 Nov 17;64(47):e202504790},
      abstract     = {Most living things on Earth - from bacteria to humans -
                      must migrate in some way to find favourable conditions.
                      Therefore, they nearly all use chemotaxis, in which their
                      movement is steered by a gradient of chemicals. Chemotaxis
                      is fundamental to many processes that control our
                      well-being, including inflammation, neuronal patterning,
                      wound healing, tumour spread in cancer, even embryogenesis.
                      Understanding it is a key goal for biologists. Despite the
                      fact that many basic principles appear to have been
                      conserved throughout evolution, most research has focused on
                      understanding the molecular mechanisms that control signal
                      processing and locomotion. Cell signaling - cells responding
                      to time-varying external signals - underlies almost all
                      biological processes at the cellular scale. Chemotaxis of
                      single cells provides particularly amenable model systems
                      for quantitative cell signaling studies, even in the
                      presence of noise and fluctuations, because the output, the
                      cell's motility response, is directly observable. However,
                      the different scientific disciplines involved in chemotaxis
                      research rarely overlap, so biologists, physicists and
                      mathematicians interact far too infrequently, methodologies
                      and models differ and commonalities are often overlooked,
                      such as the possible influence of physical or environmental
                      conditions, which has been largely neglected.},
      subtyp        = {Review Article},
      keywords     = {Active colloids (Other) / Bacteria (Other) / Chemotaxis
                      (Other) / Dictyostelium (Other)},
      cin          = {E300},
      ddc          = {540},
      cid          = {I:(DE-He78)E300-20160331},
      pnm          = {315 - Bildgebung und Radioonkologie (POF4-315)},
      pid          = {G:(DE-HGF)POF4-315},
      typ          = {PUB:(DE-HGF)16},
      pubmed       = {pmid:41147556},
      doi          = {10.1002/anie.202504790},
      url          = {https://inrepo02.dkfz.de/record/305571},
}