Journal Article (Review Article)

DKFZ-2025-02233

http://join2-wiki.gsi.de/foswiki/pub/Main/Artwork/join2_logo100x88.png Perspective on Interdisciplinary Approaches on Chemotaxis.

Simmchen, J. ; Gordon, D. ; MacKenzie, J. ; Pagonabarraga, I. ; Roggatz, C. C. ; Endres, R. G. ; Xiao, Z. ; Friedrich, B. M. ; Qiu, T.DKFZ* ; Painter, K. J. ; Golestanian, R. ; Contini, C. ; Ucar, M. C. ; Yossifon, G. ; Sommer, J. U. ; Rappel, W.-J. ; Wan, K. Y. ; Armitage, J. ; Insall, R.

2025
Wiley-VCH Weinheim

This record in other databases:  

Please use a persistent id in citations: doi:10.1002/anie.202504790

Abstract: Most living things on Earth - from bacteria to humans - must migrate in some way to find favourable conditions. Therefore, they nearly all use chemotaxis, in which their movement is steered by a gradient of chemicals. Chemotaxis is fundamental to many processes that control our well-being, including inflammation, neuronal patterning, wound healing, tumour spread in cancer, even embryogenesis. Understanding it is a key goal for biologists. Despite the fact that many basic principles appear to have been conserved throughout evolution, most research has focused on understanding the molecular mechanisms that control signal processing and locomotion. Cell signaling - cells responding to time-varying external signals - underlies almost all biological processes at the cellular scale. Chemotaxis of single cells provides particularly amenable model systems for quantitative cell signaling studies, even in the presence of noise and fluctuations, because the output, the cell's motility response, is directly observable. However, the different scientific disciplines involved in chemotaxis research rarely overlap, so biologists, physicists and mathematicians interact far too infrequently, methodologies and models differ and commonalities are often overlooked, such as the possible influence of physical or environmental conditions, which has been largely neglected.

Keyword(s): Active colloids ; Bacteria ; Chemotaxis ; Dictyostelium

Note: 2025 Nov 17;64(47):e202504790

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Contributing Institute(s):

1. Smart Technologies für die Tumortherapie (E300)

Research Program(s):

1. 315 - Bildgebung und Radioonkologie (POF4-315) (POF4-315)

Appears in the scientific report 2025

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Database coverage:
; Chemical Reactions ; Clarivate Analytics Master Journal List ; Current Contents - Life Sciences ; Current Contents - Physical, Chemical and Earth Sciences ; DEAL Wiley ; Ebsco Academic Search ; Essential Science Indicators ; IF >= 15 ; Index Chemicus ; JCR ; Nationallizenz ; SCOPUS ; Science Citation Index Expanded ; Web of Science Core Collection

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