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@ARTICLE{Simon:305603,
      author       = {N. Simon$^*$ and S. Volz$^*$ and J. Rios de los Rios
                      Reséndiz$^*$ and T. Wedig$^*$ and S. H. Montigel$^*$ and N.
                      Schwarz$^*$ and K. Richter$^*$ and D. Helm$^*$ and M.
                      Neßling$^*$ and L. Zielske$^*$ and J. Berker$^*$ and S.
                      Russeck$^*$ and M. Mauermann$^*$ and W.-K. Hofmann and S. M.
                      Pfister$^*$ and K. W. Pajtler$^*$ and K. K. Maaß$^*$ and K.
                      Clemm von Hohenberg$^*$},
      title        = {{P}reanalytical framework for routine clinical use of
                      liquid biopsies: combining {EV}s and cf{DNA}},
      journal      = {Extracellular vesicles and circulating nucleic acids},
      volume       = {6},
      issn         = {2767-6641},
      address      = {Los Angeles},
      publisher    = {[Verlag nicht ermittelbar]},
      reportid     = {DKFZ-2025-02253},
      pages        = {626 - 650},
      year         = {2025},
      note         = {Extracellular Vesicles and Circulating Nucleic Acids
                      2025;6:626-650 / #EA:B062#LA:B470#},
      abstract     = {Aim: Liquid biopsies hold significant potential for the
                      minimally invasive diagnosis of tumors and other
                      diseases.While the clinical application of cell-free DNA
                      (cfDNA) methodologies is emerging, the implementation of
                      tumor-derived extracellular vesicles (EVs) as validated
                      biomarkers is hindered by substantial preanalytical
                      variations. In this work, we standardized the preanalytical
                      procedures of blood collection for subsequent serial
                      isolation of plasma cfDNA and EVs from a single blood
                      collection tube.},
      cin          = {B062 / HD01 / B470 / W230 / W120},
      cid          = {I:(DE-He78)B062-20160331 / I:(DE-He78)HD01-20160331 /
                      I:(DE-He78)B470-20160331 / I:(DE-He78)W230-20160331 /
                      I:(DE-He78)W120-20160331},
      pnm          = {312 - Funktionelle und strukturelle Genomforschung
                      (POF4-312)},
      pid          = {G:(DE-HGF)POF4-312},
      typ          = {PUB:(DE-HGF)16},
      doi          = {10.20517/evcna.2025.44},
      url          = {https://inrepo02.dkfz.de/record/305603},
}