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@ARTICLE{Brhlmann:306518,
author = {S. A. Brühlmann and M. Walther and N. Zhutova and K.
Kopka$^*$ and M. Kreller},
title = {{F}rom bench to batch: scaling up copper-67 production via
the 70 {Z}n(p,α) 67 {C}u nuclear reaction},
journal = {Radiochimica acta},
volume = {nn},
issn = {0033-8230},
address = {Berlin},
publisher = {De Gruyter},
reportid = {DKFZ-2025-02583},
pages = {nn},
year = {2025},
note = {epub},
abstract = {In this work, we present a novel radiochemical separation
method for isolating radiocopper from zinc targets, in
particular optimized for use in compact cyclotron systems
for Cu-67 production from Zn-70. We further report - for the
first time using compact cyclotrons - Cu-67 yields in the
GBq range, with molar activities reaching 5-35 $\%$ of the
theoretical maximum. In addition, high radionuclidic
purities comparable to previously described values are
presented (>99 $\%).$ The complete workflow, including
target preparation, irradiation parameters, post-irradiation
handling, and quality control, is described in detail,
offering a robust and reproducible framework for advancing a
reliable Cu-67 production in decentralized settings.},
cin = {DD01},
ddc = {610},
cid = {I:(DE-He78)DD01-20160331},
pnm = {899 - ohne Topic (POF4-899)},
pid = {G:(DE-HGF)POF4-899},
typ = {PUB:(DE-HGF)16},
doi = {10.1515/ract-2025-0083},
url = {https://inrepo02.dkfz.de/record/306518},
}