Journal Article

DKFZ-2025-02583

http://join2-wiki.gsi.de/foswiki/pub/Main/Artwork/join2_logo100x88.png From bench to batch: scaling up copper-67 production via the 70 Zn(p,α) 67 Cu nuclear reaction

Brühlmann, S. A. ; Walther, M. ; Zhutova, N. ; Kopka, K.DKFZ* ; Kreller, M.

2025
˜Deœ Gruyter Berlin

Abstract: In this work, we present a novel radiochemical separation method for isolating radiocopper from zinc targets, in particular optimized for use in compact cyclotron systems for Cu-67 production from Zn-70. We further report - for the first time using compact cyclotrons - Cu-67 yields in the GBq range, with molar activities reaching 5-35 % of the theoretical maximum. In addition, high radionuclidic purities comparable to previously described values are presented (>99 %). The complete workflow, including target preparation, irradiation parameters, post-irradiation handling, and quality control, is described in detail, offering a robust and reproducible framework for advancing a reliable Cu-67 production in decentralized settings.

Note: epub

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Contributing Institute(s):

1. DKTK Koordinierungsstelle Dresden (DD01)

Research Program(s):

1. 899 - ohne Topic (POF4-899) (POF4-899)

Appears in the scientific report 2025

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Database coverage:
; Clarivate Analytics Master Journal List ; Current Contents - Physical, Chemical and Earth Sciences ; Essential Science Indicators ; IF < 5 ; JCR ; SCOPUS ; Science Citation Index Expanded ; Web of Science Core Collection

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