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@ARTICLE{Mller:306665,
      author       = {R. Möller and B. Kamp and P. Leja and T. A. Thiel and E.
                      Bechler and H.-J. Wittsack and G. Antoch and A. Nagel$^*$
                      and L. M. Wilms and M. Frenken and A. Müller-Lutz},
      title        = {{E}valuation of {P}artial {V}olume {C}orrection
                      {T}echniques for {S}odium {MRI} of the {A}chilles {T}endon.},
      journal      = {Magnetic resonance in medicine},
      volume       = {95},
      number       = {4},
      issn         = {1522-2594},
      address      = {New York, NY [u.a.]},
      publisher    = {Wiley-Liss},
      reportid     = {DKFZ-2025-02658},
      pages        = {2180-2193},
      year         = {2026},
      note         = {2026 Apr;95(4):2180-2193},
      abstract     = {To evaluate partial volume correction (PVC) techniques for
                      sodium MRI of the Achilles tendon in situ and in vivo.Five
                      PVC methods were evaluated including a volume ratio of the
                      proton and sodium segmentations (PSSR), a modified least
                      trimmed square (3D-mLTS) linear regression, a geometric
                      transfer matrix (GTM) approach, a single target correction
                      (STC), and a novel estimated single target correction
                      (eSTC). Their performance was tested using simulated data
                      and 3 T MR data of two volunteers' Achilles tendons acquired
                      at different resolutions: 1.5, 2.0, 3.0, and 4.5 mm3. Since
                      there was no in vivo ground truth, the highest-resolution
                      apparent tissue sodium contents (aTSC) were used.In the
                      simulation, all PVC methods reduced the difference between
                      the actual and calculated concentrations and were 11.69 ±
                      6.17 mM without PVC, 4.90 ± 5.40 mM with the PSSR, 4.86 ±
                      5.19 mM with the mLTS, 1.72 ± 4.13 mM with the GTM, 0.36 ±
                      1.77 mM with STC and 0.26 ± 1.63 mM with the eSTC. In vivo,
                      the difference in aTSCs between the lower and the highest
                      resolution decreased with all PVCs ranging from 3.6 to 38.8
                      mM without PVC, 2.8-20.4 mM with PSSR, 4.5-25.9 mM with
                      mLTS, 0.9-7.8 mM with GTM, 0.1-23.8 mM with STC, and 0.7-7.7
                      mM with eSTC.PVC generally improved the accuracy of aTSC
                      calculations. The newly introduced eSTC produced the most
                      accurate results for the Achilles tendon.},
      keywords     = {23Na‐MRI (Other) / Achilles tendon (Other) / partial
                      volume correction (Other) / sodium MRI (Other) / sodium
                      concentration (Other)},
      cin          = {E020},
      ddc          = {610},
      cid          = {I:(DE-He78)E020-20160331},
      pnm          = {315 - Bildgebung und Radioonkologie (POF4-315)},
      pid          = {G:(DE-HGF)POF4-315},
      typ          = {PUB:(DE-HGF)16},
      pubmed       = {pmid:41310405},
      doi          = {10.1002/mrm.70208},
      url          = {https://inrepo02.dkfz.de/record/306665},
}