Journal Article (Editorial)

DKFZ-2025-03016

http://join2-wiki.gsi.de/foswiki/pub/Main/Artwork/join2_logo100x88.png Risk-adapted Prostate Cancer Screening Achieves Mammography-like Benefits: Evidence and Implications for Europe.

Carlsson, S. (First author)DKFZ* ; Krilaviciute, A.DKFZ* ; Al-Monajjed, R.DKFZ* ; Seibold, P.DKFZ* ; Kuczyk, M. ; Gschwend, J. E. ; Debus, J. ; Antoch, G. ; Schimmöller, L. ; Schlemmer, H.-P.DKFZ* ; Kristiansen, G. ; Kaaks, R.DKFZ* ; Becker, N.DKFZ* ; Albers, P.DKFZ* ; Group, P. S. (Collaboration Author)

2026
Elsevier Science Amsterdam [u.a.]

Abstract: Using Germany as a case example, a comparison between organized mammography screening and contemporary, risk-adapted screening for prostate cancer suggests that prostate-specific antigen-based early detection with incorporation of magnetic resonance imaging and active surveillance can achieve benefits comparable to those of mammography while addressing previous concerns about overdiagnosis and overtreatment. Findings from the PROBASE trial support the potential of such an approach to provide a favorable balance between benefit and harm when initiated at younger ages.

Note: #EA:C070#LA:C130# / 2026 Mar;89(3):193-195

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Contributing Institute(s):

1. C070 Klinische Epidemiologie der Krebsfrüherkennung (C070)
2. Personalisierte Früherkennung des Prostatakarzinoms (C130)
3. E010 Radiologie (E010)
4. Epidemiologie von Krebs (C020)

Research Program(s):

1. 313 - Krebsrisikofaktoren und Prävention (POF4-313) (POF4-313)

Appears in the scientific report 2025

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Database coverage:
; BIOSIS Previews ; Biological Abstracts ; Clarivate Analytics Master Journal List ; Current Contents - Clinical Medicine ; Ebsco Academic Search ; Essential Science Indicators ; IF >= 20 ; JCR ; National-Konsortium ; SCOPUS ; Science Citation Index Expanded ; Web of Science Core Collection

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