Journal Article

DKFZ-2026-00239

http://join2-wiki.gsi.de/foswiki/pub/Main/Artwork/join2_logo100x88.png ABC8 Consensus: Assessment by a German Group of Experts.

Ditsch, N. ; Untch, M. ; Fasching, P. A. ; Briest, S. ; Ettl, J. ; Haidinger, R. ; Lüftner, D. ; Maurer, C.DKFZ* ; Müller, V. ; Park-Simon, T.-W. ; Ruckhäberle, E. ; Schem, C. ; Schumacher-Wulf, E. ; Harbeck, N. ; Wuerstlein, R.

2026
Karger Basel

Abstract: The 'International Consensus Conference for Advanced Breast Cancer' was initiated with the rationale to standardize treatment of advanced breast cancer (ABC) based on available evidence. The aim was to ensure that all ABC patients worldwide receive adequate treatment and get access to new diagnostic, therapeutic, and supportive options.Since the beginning ABC Consensus Conference has been organized in Lisbon/Portugal. The 8th International Consensus Conference for ABC (ABC8) took place there from November 4th to 8th, 2025, and focused not only on metastatic disease but also on locally advanced and inflammatory breast cancer (BC). Special topics were new drugs and new therapies with promising results in randomized clinical trials. Not all of them are currently approved by FDA (Food and Drug Administration) or EMA (European Medicines Agency) for the indication in which the study was conducted. As in previous years, patient advocates from around the world were integrated into the ABC Conference and contributed substantially to the consensus.A German BC expert panel comments on the voting results of the ABC8 panelists regarding their relevance for routine clinical practice in Germany. As with previous meetings, the ABC8 votes focused on modified or new statements. Statements not modified for the ABC8 consensus remain valid. The German comments are always based on the current recommendations of the 'Breast Committee' of the Gynecological Oncology Working Group (Arbeitsgemeinschaft Gynäkologische Onkologie, AGO Mamma).

Keyword(s): Antibody-drug conjugates ; Brain imaging ; Oral selective estrogen receptor degraders ; Precision medicine ; Systemic therapy

Note: #NCTZFB9# / epub

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Contributing Institute(s):

1. Koordinierungsstelle NCT Heidelberg (HD02)

Research Program(s):

1. 899 - ohne Topic (POF4-899) (POF4-899)

Appears in the scientific report 2026

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Database coverage:
; Clarivate Analytics Master Journal List ; Essential Science Indicators ; IF < 5 ; JCR ; National-Konsortium ; SCOPUS ; Science Citation Index Expanded ; Web of Science Core Collection

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