TY  - JOUR
AU  - Becker, Esther B E
AU  - Mayer, Simone
AU  - Kutscher, Lena
TI  - Generating cerebellar organoids from pluripotent stem cells.
JO  - Disease models & mechanisms
VL  - 19
IS  - 1
SN  - 1754-8403
CY  - Cambridge
PB  - Company of Biologists Limited
M1  - DKFZ-2026-00260
SP  - dmm052478
PY  - 2026
N1  - #LA:B430#
AB  - Cerebellar organoids present promising tools for the modelling of human cerebellar development and diseases. As this young field grows, robust standards and transparent reporting practices are needed to ensure the reproducibility and utility of the generated cerebellar organoid models. Here, we summarize current approaches to generate cerebellar organoids and their applications. We suggest common quality control standards and biological readouts that should be considered in this emerging area.
KW  - Organoids: cytology
KW  - Humans
KW  - Cerebellum: cytology
KW  - Pluripotent Stem Cells: cytology
KW  - Animals
KW  - Cerebellum (Other)
KW  - Development (Other)
KW  - Disease models (Other)
KW  - Organoid (Other)
KW  - Quality control (Other)
LB  - PUB:(DE-HGF)16
C6  - pmid:41614223
DO  - DOI:10.1242/dmm.052478
UR  - https://inrepo02.dkfz.de/record/309610
ER  -