Journal Article (Review Article)

DKFZ-2026-00260

http://join2-wiki.gsi.de/foswiki/pub/Main/Artwork/join2_logo100x88.png Generating cerebellar organoids from pluripotent stem cells.

Becker, E. B. E. ; Mayer, S. ; Kutscher, L. (Last author)DKFZ*

2026
Company of Biologists Limited Cambridge

Abstract: Cerebellar organoids present promising tools for the modelling of human cerebellar development and diseases. As this young field grows, robust standards and transparent reporting practices are needed to ensure the reproducibility and utility of the generated cerebellar organoid models. Here, we summarize current approaches to generate cerebellar organoids and their applications. We suggest common quality control standards and biological readouts that should be considered in this emerging area.

Keyword(s): Organoids: cytology (MeSH) ; Humans (MeSH) ; Cerebellum: cytology (MeSH) ; Pluripotent Stem Cells: cytology (MeSH) ; Animals (MeSH) ; Cerebellum ; Development ; Disease models ; Organoid ; Quality control

Note: #LA:B430#

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Contributing Institute(s):

1. Entwicklungsbiolog. Ursprünge pädiatrischer Krebserkrankungen (B430)

Research Program(s):

1. 312 - Funktionelle und strukturelle Genomforschung (POF4-312) (POF4-312)

Appears in the scientific report 2026

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Database coverage:
; ; ; Article Processing Charges ; BIOSIS Previews ; Biological Abstracts ; Clarivate Analytics Master Journal List ; DOAJ Seal ; Essential Science Indicators ; Fees ; IF < 5 ; JCR ; PubMed Central ; SCOPUS ; Science Citation Index Expanded ; Web of Science Core Collection

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