A013

Recent Publications

All known publications ...
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http://join2-wiki.gsi.de/foswiki/pub/Main/Artwork/join2_logo100x88.png Journal Article White, M. ; Mills, M. L. ; Millett, L. M. ; Gilroy, K. ; Hong, Y. ; Zeiger, L. B. ; Simpson, R. J. ; Corry, S. M. ; Ligeza, A. ; Lannagan, T. R. M. ; Susanti, S. ; Ridgway, R. A. ; Yazgili, A. S. ; Grzesiak, L. ; Amirkhah, R. ; Ford, C. A. ; Vlahov, N. ; Tovell, H. ; Officer-Jones, L. ; Ficken, C. ; Pennie, R. ; Najumudeen, A. K. ; Raven, A. ; Nasreddin, N. ; Chauhan, E. ; Papanastasiou, A. S. ; Nixon, C. ; Morrison, V. ; Jackstadt, R.-F.DKFZ* ; Graham, J. S. ; Miller, C. J. ; Ross, S. J. ; Barry, S. T. ; Pavet, V. ; Wilson, R. H. ; Le Quesne, J. ; Dunne, P. D. ; Tejpar, S. ; Leedham, S. ; Campbell, A. D. ; Sansom, O. J.
MAPK-driven epithelial cell plasticity drives colorectal cancer therapeutic resistance.
Nature 650(8102), 748-758 (2026) [10.1038/s41586-025-09916-w]2026   BibTeX | EndNote: XML, Text | RIS

http://join2-wiki.gsi.de/foswiki/pub/Main/Artwork/join2_logo100x88.png Journal Article Gobits, R. ; Schleußner, N. (First author)DKFZ* ; Oliver, G. R. ; Rutenberg Schoenberg, M. ; de Jesus Domingues, A. M. ; Ramkumar, P. ; Suen, S. W. F. ; Koomen, M. P. M. ; Paolucci, F. ; Martens, K. ; Guiseris Martinez, A.DKFZ* ; Volk, J.DKFZ* ; Artmann, C.DKFZ* ; Mastel, M.DKFZ* ; Ouyang, K.DKFZ* ; Kloor, M. ; Bankaitis, E. D. ; Stoub, H. E. ; Puschhof, J.DKFZ* ; Brown, K. ; Pretzer, S. ; Nelson, D. A. ; Struminger, E. ; Zessin, A. ; Brown, A. ; Evans, C. ; Yetsko, D. ; Harrington, M. ; Salg, G. ; Schneider, M. ; Schmidt, T. ; Helman, E. ; Plenker, D. ; Barnett, C. ; Jones, R. T. ; Köhler, B. C.DKFZ* ; Driehuis, E. ; Jackstadt, R.-F. (Last author)DKFZ*
Functional Precision Medicine Using MicroOrganoSpheres for Treatment Response Prediction in Advanced Colorectal Cancer.
JCO precision oncology 10(10), e2500501 (2026) [10.1200/PO-25-00501]2026   BibTeX | EndNote: XML, Text | RIS

http://join2-wiki.gsi.de/foswiki/pub/Main/Artwork/join2_logo100x88.png Journal Article Wouters, V. M. ; Helderman, R. F. C. P. A. ; Cameron, K. ; van der Hooff, S. R. ; Torang, A. ; van den Bergh, S. ; Jackstadt, R.DKFZ* ; Sansom, O. J. ; van Neerven, S. M. ; Medema, J. P.
CDX2 downregulation regulates intrinsic WNT pathway activation, dictating metastasis in APC and CTNNB1 wildtype colorectal cancer.
Oncogene 44(25), 2091-2102 (2025) [10.1038/s41388-025-03365-5]2025   BibTeX | EndNote: XML, Text | RIS

http://join2-wiki.gsi.de/foswiki/pub/Main/Artwork/join2_logo100x88.png Journal Article Škapik, I. P. ; Giacomelli, C. ; Hahn, S. ; Deinlein, H. ; Gallant, P. ; Diebold, M. ; Biayna, J. ; Hendricks, A. ; Olimski, L. ; Otto, C. ; Kastner, C. ; Wolf, E. ; Schülein-Völk, C. ; Maurus, K. ; Rosenwald, A. ; Schleussner, N.DKFZ* ; Jackstadt, R.-F.DKFZ* ; Schlegel, N. ; Germer, C.-T. ; Bushell, M. ; Eilers, M. ; Schmidt, S. ; Wiegering, A.
Maintenance of p-eIF2α levels by the eIF2B complex is vital for colorectal cancer.
The EMBO journal 44, 2075 - 2105 (2025) [DOI:10.1038/s44318-025-00381-9]2025   BibTeX | EndNote: XML, Text | RIS

http://join2-wiki.gsi.de/foswiki/pub/Main/Artwork/join2_logo100x88.png Journal Article Torang, A. ; Kirov, A. B. ; Lammers, V. ; Cameron, K. ; Wouters, V. M. ; Jackstadt, R. F.DKFZ* ; Lannagan, T. R. M. ; de Jong, J. H. ; Koster, J. ; Sansom, O. ; Medema, J. P.
Enterocyte-like differentiation defines metabolic gene signatures of CMS3 colorectal cancers and provides therapeutic vulnerability.
Nature Communications 16(1), 264 (2025) [10.1038/s41467-024-55574-3]2025     Files  Fulltext by Pubmed Central BibTeX | EndNote: XML, Text | RIS

http://join2-wiki.gsi.de/foswiki/pub/Main/Artwork/join2_logo100x88.png Journal Article Köhler, B. C.DKFZ* ; Haag, G. M. (First author)DKFZ* ; Le Cornet, L.DKFZ* ; Hoffmeister-Wittmann, P.DKFZ* ; Schmidt, M.DKFZ* ; Manjunath, A. ; Vaquero-Siguero, N.DKFZ* ; Jenzer, M. ; Gimmel, M. ; Stahler, A. ; Stein, A. ; Reichert, M. ; Kasper, S. ; Bitzer, M. ; Jäger, D.DKFZ* ; Springfeld, C. ; Weber, T. F.DKFZ* ; Fröhling, S.DKFZ* ; Steindorf, K.DKFZ* ; Trumpp, A.DKFZ* ; Schlenk, R. F. ; Jackstadt, R.-F. (Last author)DKFZ*
TROPHIT1—a randomized, open-label, multicenter, phase II/III trial of sacituzumab govitecan compared to standard of care in metastatic colorectal cancer patients
ESMO gastrointestinal oncology 7, 100118 (2025) [10.1016/j.esmogo.2024.100118]2025     Files BibTeX | EndNote: XML, Text | RIS

http://join2-wiki.gsi.de/foswiki/pub/Main/Artwork/join2_logo100x88.png Journal Article Xu, K. ; Kessler, A. ; Nichetti, F. (First author)DKFZ* ; Hoffmeister-Wittmann, P. ; Scherr, A.-L. ; Nader, L. ; Kelmendi, E. ; Schmitt, N. ; Schwab, M. ; García-Beccaria, M.DKFZ* ; Sobol, B. ; Nieto, O. A. ; Isele, H. ; Gärtner, U. ; Vaquero-Siguero, N.DKFZ* ; Volk, J.DKFZ* ; Korell, F.DKFZ* ; Mock, A.DKFZ* ; Heide, D.DKFZ* ; Ramadori, P.DKFZ* ; Lenoir, B.DKFZ* ; Albrecht, T. ; Hüllein, J.DKFZ* ; Jäger, D.DKFZ* ; Fröhling, S.DKFZ* ; Springfeld, C. ; Jackstadt, R.-F.DKFZ* ; Heikenwälder, M.DKFZ* ; Dill, M.DKFZ* ; Roessler, S. ; Goeppert, B. ; Köhler, B. C.DKFZ*
Lymphotoxin beta-activated LTBR/NIK/RELB axis drives proliferation in cholangiocarcinoma.
Liver international 44(11), 2950-2963 (2024) [10.1111/liv.16069]2024     Files BibTeX | EndNote: XML, Text | RIS

http://join2-wiki.gsi.de/foswiki/pub/Main/Artwork/join2_logo100x88.png Journal Article (Review Article) Fey, S. K. (First author)DKFZ* ; Vaquero-Siguero, N. (First author)DKFZ* ; Jackstadt, R.-F. (Last author)DKFZ*
Dark force rising: Reawakening and targeting of fetal-like stem cells in colorectal cancer.
Cell reports 43(6), 114270 (2024) [10.1016/j.celrep.2024.114270]2024     Files BibTeX | EndNote: XML, Text | RIS

http://join2-wiki.gsi.de/foswiki/pub/Main/Artwork/join2_logo100x88.png Journal Article/Contribution to a conference proceedings/Contribution to a book Maier, A. (Editor) ; Deserno, T. M. (Editor) ; Handels, H. (Editor) ; Maier-Hein, K. (Editor)DKFZ* ; Palm, C. (Editor) ; Tolxdorff, T. (Editor) ; Eixelberger, T. ; Fang, Q. ; Zohud, B. A. ; Hackner, R. ; Jackstadt, R.DKFZ* ; Stürzl, M. ; Naschberger, E. ; Wittenberg, T.
Automated Lesion Detection in Endoscopic Imagery for Small Animal Models
2024Bildverarbeitung für die Medizin 2024 / Maier, Andreas (Editor) [https://orcid.org/0000-0002-9550-5284] ; Wiesbaden : Springer Fachmedien Wiesbaden, 2024, Chapter 54 ; ISSN: 1431-472X=2628-8958 ; ISBN: 978-3-658-44036-7=978-3-658-44037-4 ; doi:10.1007/978-3-658-44037-4
German Conference on Medical Image Computing, BVM 2024, ErlangenErlangen, Germany, 24 Mar 2024 - 24 Mar 20242024-03-242024-03-24 Informatik aktuell 190 - 195 (2024) [10.1007/978-3-658-44037-4_54]2024   BibTeX | EndNote: XML, Text | RIS

http://join2-wiki.gsi.de/foswiki/pub/Main/Artwork/join2_logo100x88.png Journal Article Malviya, G. ; Lannagan, T. R. M. ; Johnson, E. ; Mackintosh, A. ; Bielik, R. ; Peters, A. ; Soloviev, D. ; Brown, G. ; Jackstadt, R.-F.DKFZ* ; Nixon, C. ; Gilroy, K. ; Campbell, A. ; Sansom, O. J. ; Lewis, D. Y.
Noninvasive Stratification of Colon Cancer by Multiplex PET Imaging.
Clinical cancer research 30(8), 1518-1529 (2024) [10.1158/1078-0432.CCR-23-1063]2024     Files BibTeX | EndNote: XML, Text | RIS

All known publications ...
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