Journal Article

DKFZ-2017-03690

http://join2-wiki.gsi.de/foswiki/pub/Main/Artwork/join2_logo100x88.png Optimization approaches to volumetric modulated arc therapy planning.

Unkelbach, J. ; Bortfeld, T. ; Craft, D. ; Alber, M. ; Bangert, M.DKFZ* ; Bokrantz, R. ; Chen, D. ; Li, R. ; Xing, L. ; Men, C. ; Nill, S. ; Papp, D. ; Romeijn, E. ; Salari, E.

2015
New York, NY

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Please use a persistent id in citations: doi:10.1118/1.4908224

Abstract: Volumetric modulated arc therapy (VMAT) has found widespread clinical application in recent years. A large number of treatment planning studies have evaluated the potential for VMAT for different disease sites based on the currently available commercial implementations of VMAT planning. In contrast, literature on the underlying mathematical optimization methods used in treatment planning is scarce. VMAT planning represents a challenging large scale optimization problem. In contrast to fluence map optimization in intensity-modulated radiotherapy planning for static beams, VMAT planning represents a nonconvex optimization problem. In this paper, the authors review the state-of-the-art in VMAT planning from an algorithmic perspective. Different approaches to VMAT optimization, including arc sequencing methods, extensions of direct aperture optimization, and direct optimization of leaf trajectories are reviewed. Their advantages and limitations are outlined and recommendations for improvements are discussed.

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Contributing Institute(s):

1. Medizinische Physik in der Strahlentherapie (E040)

Research Program(s):

1. 315 - Imaging and radiooncology (POF3-315) (POF3-315)

Appears in the scientific report 2015

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Database coverage:
; Current Contents - Clinical Medicine ; Current Contents - Life Sciences ; Ebsco Academic Search ; IF < 5 ; JCR ; SCOPUS ; Science Citation Index ; Science Citation Index Expanded ; Thomson Reuters Master Journal List ; Web of Science Core Collection

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