A380
NWG Molekulare Leukämogenese
Also known as:A380; Nachwuchsgruppe Molekulare Leukämogenese
ID | I:(DE-He78)A380-20160331 |
⇦ G240
Recent Publications
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Journal Article
Rein, A. ; Geron, I. ; Kugler, E. ; Fishman, H. ; Gottlieb, E. ; Abramovich, I. ; Giladi, A. ; Amit, I. ; Mulet-Lazaro, R. ; Delwel, R. ; Gröschel, S.DKFZ* ; Levin-Zaidman, S. ; Dezorella, N. ; Holdengreber, V. ; Rao, T. N. ; Yacobovich, J. ; Steinberg-Shemer, O. ; Huang, Q.-H. ; Tan, Y. ; Chen, S.-J. ; Izraeli, S. ; Birger, Y.
Cellular and metabolic characteristics of pre-leukemic hematopoietic progenitors with GATA2 haploinsufficiency.
Haematologica 108(9), 2316-2330 (2023) [10.3324/haematol.2022.279437]2023
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Leichsenring, J. ; Vladimirova, V. ; Solbach, C. ; Karn, T. ; Ataseven, B. ; Sinn, B. V. ; Barinoff, J. ; Müller, V. ; Blohmer, J.-U. ; Schem, C. ; Engels, K. ; Marmé, F. ; Fisseler-Eckhoff, A. ; Fasching, P. A. ; Stickeler, E. ; van Mackelenbergh, M. ; Denkert, C. ; Stenzinger, A. ; Loibl, S. ; Gröschel, S. (Last author)DKFZ*
EVI1 expression in early-stage breast cancer patients treated with neoadjuvant chemotherapy.
BMC cancer 22(1), 1040 (2022) [10.1186/s12885-022-10109-1]2022
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Ottema, S. ; Mulet-Lazaro, R. ; Erpelinck-Verschueren, C. ; van Herk, S. ; Havermans, M. ; Arricibita Varea, A. ; Vermeulen, M. ; Beverloo, H. B. ; Gröschel, S.DKFZ* ; Haferlach, T. ; Haferlach, C. ; J Wouters, B. ; Bindels, E. ; Smeenk, L. ; Delwel, R.
The leukemic oncogene EVI1 hijacks a MYC super-enhancer by CTCF-facilitated loops.
Nature Communications 12(1), 5679 (2021) [10.1038/s41467-021-25862-3]2021
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Journal Article
Kiehlmeier, S. (First author)DKFZ* ; Rafiee, M.-R. ; Bakr, A. M. A.DKFZ* ; Mika, J.DKFZ* ; Kruse, S.DKFZ* ; Müller, J.DKFZ* ; Schweiggert, S.DKFZ* ; Herrmann, C. ; Sigismondo, G.DKFZ* ; Schmezer, P.DKFZ* ; Krijgsveld, J.DKFZ* ; Gröschel, S. (Last author)DKFZ*
Identification of therapeutic targets of the hijacked super-enhancer complex in EVI1-rearranged leukemia.
Leukemia 35(11), 3127-3138 (2021) [10.1038/s41375-021-01235-z]2021
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Journal Article (Letter)
Mika, J. (First author)DKFZ* ; Ottema, S. ; Kiehlmeier, S.DKFZ* ; Kruse, S.DKFZ* ; Smeenk, L. ; Müller, J.DKFZ* ; Schweiggert, S.DKFZ* ; Herrmann, C. ; Sanders, M. ; Delwel, R. ; Gröschel, S. (Last author)DKFZ*
Derepression of retroelements in acute myeloid leukemia with 3q aberrations.
Haematologica 106(8), 2269-2273 (2021) [10.3324/haematol.2020.277400]2021
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Vu, T. ; Straube, J. ; Porter, A. H. ; Bywater, M. ; Song, A. ; Ling, V. ; Cooper, L. ; Pali, G. ; Bruedigam, C. ; Jacquelin, S. ; Green, J. ; Magor, G. ; Perkins, A. ; Chalk, A. M. ; Walkley, C. R. ; Heidel, F. H. ; Mukhopadhyay, P. ; Cloonan, N. ; Gröschel, S.DKFZ* ; Mallm, J.-P.DKFZ* ; Fröhling, S.DKFZ* ; Scholl, C.DKFZ* ; Lane, S. W.
Hematopoietic stem and progenitor cell-restricted Cdx2 expression induces transformation to myelodysplasia and acute leukemia.
Nature Communications 11(1), 3021 (2020) [10.1038/s41467-020-16840-2]2020
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Journal Article
Ptasinska, A. ; Pickin, A. ; Assi, S. A. ; Chin, P. S. ; Ames, L. ; Avellino, R. ; Gröschel, S.DKFZ* ; Delwel, R. ; Cockerill, P. N. ; Osborne, C. S. ; Bonifer, C.
RUNX1-ETO Depletion in t(8;21) AML Leads to C/EBPα- and AP-1-Mediated Alterations in Enhancer-Promoter Interaction.
Cell reports 28(12), 3022 - 3031.e7 (2019) [10.1016/j.celrep.2019.08.040]2019
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Journal Article
Gröschel, S. (First author)DKFZ* ; Hübschmann, D. (First author)DKFZ* ; Raimondi, F. ; Horak, P.DKFZ* ; Warsow, G.DKFZ* ; Fröhlich, M.DKFZ* ; Klink, B. ; Gieldon, L.DKFZ* ; Hutter, B.DKFZ* ; Kleinheinz, K.DKFZ* ; Bonekamp, D.DKFZ* ; Marschal, O. ; Chudasama, P.DKFZ* ; Mika, J.DKFZ* ; Groth, M. ; Uhrig, S.DKFZ* ; Krämer, S.DKFZ* ; Heining, C.Extern* ; Heilig, C.DKFZ* ; Richter, D.DKFZ* ; Reisinger, E.DKFZ* ; Pfütze, K.DKFZ* ; Eils, R.DKFZ* ; Wolf, S.DKFZ* ; von Kalle, C.DKFZ* ; Brandts, C.DKFZ* ; Scholl, C.DKFZ* ; Weichert, W.DKFZ* ; Richter, S. ; Bauer, S.DKFZ* ; Penzel, R.DKFZ* ; Schröck, E.DKFZ* ; Stenzinger, A.DKFZ* ; Schlenk, R.DKFZ* ; Brors, B.DKFZ* ; Russell, R. B. ; Glimm, H. (Last author)DKFZ* ; Schlesner, M. (Last author)DKFZ* ; Fröhling, S. (Last author)DKFZ*
Defective homologous recombination DNA repair as therapeutic target in advanced chordoma.
Nature Communications 10(1), 1635 (2019) [10.1038/s41467-019-09633-9]2019
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