D220
DKFZ -Bayer Healthcare Joint
Also known as:D220; DKFZ-Bayer Healthcare Joint Immunotherapeutics Laboratory; Immuntherapie Labor
| ID | I:(DE-He78)D220-20160331 | 
Recent Publications
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Journal Article
 Mowat, J. ;  Carretero, R.DKFZ* ;  Leder, G. ;  Aiguabella Font, N. ;  Neuhaus, R.DKFZ* ;  Berndt, S. ;  Günther, J. ;  Friberg, A. ;  Schäfer, M. ;  Briem, H. ;  Raschke, M. ;  Miyatake Ondozabal, H. ;  Buchmann, B. ;  Boemer, U. ;  Kreft, B. ;  Hartung, I. V. ;  Offringa, R. (Last author)DKFZ*
Discovery of BAY-405: An Azaindole-Based MAP4K1 Inhibitor for the Enhancement of T-Cell Immunity against Cancer
Journal of medicinal chemistry 67(19), 17429-17453 (2024) [10.1021/acs.jmedchem.4c01325]2024
  
 
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Journal Article
 Li, Z.-J. ;  He, B. ;  Domenichini, A. ;  Satiaputra, J. ;  Wood, K. H. ;  Lakhiani, D. D. ;  Bashaw, A. A. ;  Nilsson, L. M. ;  Li, J. ;  Bastow, E. R. ;  Johansson-Percival, A. ;  Denisenko, E. ;  Forrest, A. R. ;  Sakaram, S. ;  Carretero, R.DKFZ* ;  Hämmerling, G. J.DKFZ* ;  Nilsson, J. A. ;  Lee, G. Y. ;  Ganss, R.
Pericyte phenotype switching alleviates immunosuppression and sensitizes vascularized tumors to immunotherapy in preclinical models.
The journal of clinical investigation 134(18), e179860 (2024) [10.1172/JCI179860]2024
  
 
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Journal Article
 Kilian, M. (First author)DKFZ* ;  Sheinin, R. ;  Tan, C. L.DKFZ* ;  Friedrich, M.DKFZ* ;  Krämer, C.DKFZ* ;  Kaminitz, A. ;  Sanghvi, K.DKFZ* ;  Lindner, K.DKFZ* ;  Chih, Y.-C.DKFZ* ;  Cichon, F.DKFZ* ;  Richter, B.DKFZ* ;  Jung, S.DKFZ* ;  Jähne, K.DKFZ* ;  Ratliff, M. ;  Prins, R. M. ;  Etminan, N. ;  von Deimling, A.DKFZ* ;  Wick, W.DKFZ* ;  Madi, A. ;  Bunse, L. (Last author)DKFZ* ;  Platten, M. (Last author)DKFZ*
MHC class II-restricted antigen presentation is required to prevent dysfunction of cytotoxic T cells by blood-borne myeloids in brain tumors.
Cancer cell 41(2), 235-251.e9 (2023) [10.1016/j.ccell.2022.12.007]2023
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Journal Article
 Kober, C. (First author)DKFZ* ;  Roewe, J.DKFZ* ;  Schmees, N. ;  Roese, L. ;  Roehn, U. ;  Bader, B. ;  Stoeckigt, D. ;  Prinz, F. ;  Gorjánácz, M. ;  Roider, H. G. ;  Olesch, C.DKFZ* ;  Leder, G. ;  Irlbacher, H. ;  Lesche, R. ;  Lefranc, J. ;  Oezcan-Wahlbrink, M.DKFZ* ;  Batra, A. S.DKFZ* ;  Elmadany, N.DKFZ* ;  Carretero, R.DKFZ* ;  Sahm, K.DKFZ* ;  Oezen, I.DKFZ* ;  Cichon, F.DKFZ* ;  Baumann, D.DKFZ* ;  Sadik, A.DKFZ* ;  Opitz, C. A.DKFZ* ;  Weinmann, H. ;  Hartung, I. V. ;  Kreft, B. ;  Offringa, R.DKFZ* ;  Platten, M.DKFZ* ;  Gutcher, I.
Targeting the aryl hydrocarbon receptor (AhR) with BAY 2416964: a selective small molecule inhibitor for cancer immunotherapy.
Journal for ImmunoTherapy of Cancer 11(11), e007495 (2023) [10.1136/jitc-2023-007495]2023
  
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Journal Article (Letter)
 Steinfass, T. (First author)DKFZ* ;  Poelchen, J.DKFZ* ;  Sun, Q.DKFZ* ;  Mastrogiulio, G.DKFZ* ;  Novak, D.DKFZ* ;  Vierthaler, M. ;  Pardo, S.DKFZ* ;  Federico, A.DKFZ* ;  Hüser, L.DKFZ* ;  Hielscher, T.DKFZ* ;  Carretero, R.DKFZ* ;  Offringa, R.DKFZ* ;  Altevogt, P.DKFZ* ;  Umansky, V.DKFZ* ;  Utikal, J. (Last author)DKFZ*
Secretogranin II influences the assembly and function of MHC class I in melanoma.
Experimental hematology & oncology 12(1), 29 (2023) [DOI: 10.1186/s40164-023-00387-1]2023
  
 
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Journal Article
 Weisshaar, N. (First author)DKFZ* ;  Wu, J.DKFZ* ;  Ming, Y.DKFZ* ;  Madi, A. A. M.DKFZ* ;  Hotz-Wagenblatt, A.DKFZ* ;  Ma, S.DKFZ* ;  Mieg, A.DKFZ* ;  Hering, M.DKFZ* ;  Zettl, F.DKFZ* ;  Mohr, K.DKFZ* ;  Schlimbach, T.DKFZ* ;  Ten Bosch, N.DKFZ* ;  Hertel, F.DKFZ* ;  Müller, L.DKFZ* ;  Byren, H.DKFZ* ;  Wang, M.DKFZ* ;  Borgers, H.DKFZ* ;  Munz, M.DKFZ* ;  Schmitt, L.DKFZ* ;  van der Hoeven, F.DKFZ* ;  Kloz, U.DKFZ* ;  Carretero, R.DKFZ* ;  Schleußner, N.DKFZ* ;  Jackstadt, R.-F.DKFZ* ;  Hofmann, I.DKFZ* ;  Cui, G. (Last author)DKFZ*
Rgs16 promotes antitumor CD8+ T cell exhaustion.
Science immunology 7(71), eabh1873 (2022) [10.1126/sciimmunol.abh1873]2022
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Journal Article (Review Article)
 Olesch, C. (First author)DKFZ* ;  Brüne, B.DKFZ* ;  Weigert, A.DKFZ*
Keep a Little Fire Burning—The Delicate Balance of Targeting Sphingosine-1-Phosphate in Cancer Immunity
International journal of molecular sciences 23(3), 1289 (2022) [10.3390/ijms23031289]2022
  
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Journal Article
 Pinkert, J. (First author)DKFZ* ;  Boehm, H.-H.DKFZ* ;  Trautwein, M. ;  Doecke, W.-D. ;  Wessel, F.DKFZ* ;  Ge, Y.DKFZ* ;  Gutierrez, E. M.DKFZ* ;  Carretero, R.DKFZ* ;  Freiberg, C. ;  Gritzan, U. ;  Luetke-Eversloh, M. ;  Golfier, S. ;  Von Ahsen, O. ;  Volpin, V. ;  Sorrentino, A. ;  Rathinasamy, A. ;  Xydia, M. ;  Lohmayer, R. ;  Sax, J. ;  Nur-Menevse, A. ;  Hussein, A. ;  Stamova, S. ;  Beckmann, G. ;  Glueck, J. M. ;  Schoenfeld, D. ;  Weiske, J. ;  Zopf, D. ;  Offringa, R.DKFZ* ;  Kreft, B. ;  Beckhove, P.DKFZ* ;  Willuda, J.
T cell-mediated elimination of cancer cells by blocking CEACAM6–CEACAM1 interaction
OncoImmunology 11(1), 2008110 (2022) [10.1080/2162402X.2021.2008110]2022
  
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Journal Article
 Baumann, D. (First author)DKFZ* ;  Hägele, T.DKFZ* ;  Mochayedi, J.DKFZ* ;  Drebant, J.DKFZ* ;  Vent, C.DKFZ* ;  Blobner, S.DKFZ* ;  Noll, J. H.DKFZ* ;  Nickel, I.DKFZ* ;  Schumacher, C.DKFZ* ;  Boos, S. L.DKFZ* ;  Daniel, A. S.DKFZ* ;  Wendler, S.DKFZ* ;  Volkmar, M.DKFZ* ;  Strobel, O. ;  Offringa, R. (Last author)DKFZ*
Proimmunogenic impact of MEK inhibition synergizes with agonist anti-CD40 immunostimulatory antibodies in tumor therapy.
Nature Communications 11(1), 2176 (2020) [10.1038/s41467-020-15979-2]2020
  
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Journal Article
 Bode, K. (First author)DKFZ* ;  Bujupi-Osmani, F.DKFZ* ;  Link, C.DKFZ* ;  Hein, T.DKFZ* ;  Zimmermann, S. ;  Peiris, D. ;  Jaquet, V. ;  Lepenies ;  Weyd, H.DKFZ* ;  Krammer, P. (Last author)DKFZ*
Dectin-1 binding to annexins on apoptotic cells induces peripheral immune tolerance via NADPH oxidase-2.
Cell reports 29(13), 4435-4446.e9 (2019)2019
  
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All known publications ...
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