Journal Article (Review Article)

DKFZ-2019-02950

http://join2-wiki.gsi.de/foswiki/pub/Main/Artwork/join2_logo100x88.png Greasing the Wheels of the Cancer Machine: The Role of Lipid Metabolism in Cancer

Snaebjornsson, M. T. (First author)DKFZ* ; Janaki-Raman, S. ; Schulze, A. (Last author)DKFZ*

2020
Cell Press Cambridge, Mass.

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Please use a persistent id in citations: doi:10.1016/j.cmet.2019.11.010

Abstract: Altered lipid metabolism is among the most prominent metabolic alterations in cancer. Enhanced synthesis or uptake of lipids contributes to rapid cancer cell growth and tumor formation. Lipids are a highly complex group of biomolecules that not only constitute the structural basis of biological membranes but also function as signaling molecules and an energy source. Here, we summarize recent evidence implicating altered lipid metabolism in different aspects of the cancer phenotype and discuss potential strategies by which targeting lipid metabolism could provide a therapeutic window for cancer treatment.

Note: PMID: 31813823Grants:FOR2314, SCHU2670/1bei Fragen bitte Anna Lück kontaktieren#EA:A410#LA:A410#2020 Jan 7;31(1):62-76

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Contributing Institute(s):

1. Tumor Metabolismus und Microenvironment (A410)

Research Program(s):

1. 311 - Signalling pathways, cell and tumor biology (POF3-311) (POF3-311)

Appears in the scientific report 2020

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Database coverage:
; BIOSIS Previews ; Clarivate Analytics Master Journal List ; Current Contents - Life Sciences ; IF >= 20 ; JCR ; NCBI Molecular Biology Database ; SCOPUS ; Science Citation Index ; Science Citation Index Expanded ; Web of Science Core Collection

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