Journal Article

DKFZ-2020-00781

http://join2-wiki.gsi.de/foswiki/pub/Main/Artwork/join2_logo100x88.png [Assessment of self-reported cardiovascular and metabolic diseases in the German National Cohort (GNC, NAKO Gesundheitsstudie): methods and initial results].

Jaeschke, L. ; Steinbrecher, A. ; Greiser, K. H.DKFZ* ; Dörr, M. ; Buck, T. ; Linseisen, J. ; Meisinger, C. ; Ahrens, W. ; Becher, H. ; Berger, K. ; Braun, B. ; Brenner, H.DKFZ* ; Castell, S. ; Fischer, B. ; Franzke, C.-W. ; Gastell, S. ; Günther, K. ; Hoffmann, W. ; Holleczek, B. ; Jagodzinski, A. ; Kaaks, R.DKFZ* ; Kluttig, A. ; Krause, G. ; Krist, L. ; Kuß, O. ; Lehnich, A.-T. ; Leitzmann, M. ; Lieb, W. ; Löffler, M. ; Michels, K. B. ; Mikolajczyk, R. ; Peters, A. ; Schikowski, T. ; Schipf, S. ; Schmidt, B. ; Schulze, M. ; Völzke, H. ; Willich, S. N. ; Pischon, T.

2020
Springer Heidelberg

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Please use a persistent id in citations: doi:10.1007/s00103-020-03108-9

Abstract: Data on self-reported cardiovascular and metabolic diseases are available for the first 100,000 participants of the population-based German National Cohort (GNC, NAKO Gesundheitsstudie).To describe assessment methods and the frequency of self-reported cardiovascular and metabolic diseases in the German National Cohort.Using a computer-based, standardized personal interview, 101,806 participants (20-75 years, 46% men) from 18 nationwide study centres were asked to use a predefined list to report medical conditions ever diagnosed by a physician, including cardiovascular or metabolic diseases. For the latter, we calculated sex-stratified relative frequencies and compared these with reference data.With regard to cardiovascular diseases, 3.5% of men and 0.8% of women reported to have ever been diagnosed with a myocardial infarction, 4.8% and 1.5% with angina pectoris, 3.5% and 2.5% with heart failure, 10.1% and 10.4% with cardiac arrhythmia, 2.7% and 1.8% with claudicatio intermittens, and 34.6% and 27.0% with arterial hypertension. The frequencies of self-reported diagnosed metabolic diseases were 8.1% and 5.8% for diabetes mellitus, 28.6% and 24.5% for hyperlipidaemia, 7.9% and 2.4% for gout, and 10.1% and 34.3% for thyroid diseases. Observed disease frequencies were lower than reference data for Germany.In the German National Cohort, self-reported cardiovascular and metabolic diseases diagnosed by a physician are assessed from all participants, therefore representing a data source for future cardio-metabolic research in this cohort.

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Contributing Institute(s):

1. C020 Epidemiologie von Krebs (C020)
2. C070 Klinische Epidemiologie und Alternf. (C070)
3. Präventive Onkologie (C120)

Research Program(s):

1. 323 - Metabolic Dysfunction as Risk Factor (POF3-323) (POF3-323)

Appears in the scientific report 2020

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Database coverage:
; Clarivate Analytics Master Journal List ; IF < 5 ; JCR ; Nationallizenz ; SCOPUS ; Science Citation Index Expanded ; Web of Science Core Collection

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