Journal Article

DKFZ-2022-00703

http://join2-wiki.gsi.de/foswiki/pub/Main/Artwork/join2_logo100x88.png Meat intake is associated with a higher risk of ulcerative colitis in a large European prospective cohort study.

Dong, C. ; Chan, S. S. M. ; Jantchou, P. ; Racine, A. ; Oldenburg, B. ; Weiderpass, E. ; Heath, A. K. ; Tong, T. Y. N. ; Tjønneland, A. ; Kyrø, C. ; de Mesquita, B. B. ; Kaaks, R.DKFZ* ; Katzke, V.DKFZ* ; Bergman, M. M. ; Boeing, H. ; Palli, D. ; Masala, G. ; Tumino, R. ; Sacerdote, C. ; Colorado-Yohar, S. M. ; Sánchez, M.-J. ; Grip, O. ; Lindgren, S. ; Luben, R. ; Huybrechts, I. ; Gunter, M. J. ; Mahamat-Saleh, Y. ; Boutron-Ruault, M.-C. ; Carbonnel, F.

2022
Academic Journals Nairobi, Kenya

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Please use a persistent id in citations: doi:10.1093/ecco-jcc/jjac054

Abstract: We aimed to investigate the association between protein intake and risk of inflammatory bowel disease (IBD) in the European Prospective Investigation into Cancer and Nutrition.413 593 participants from eight European countries were included. Dietary data were collected at baseline from validated food frequency questionnaires. Dietary data were calibrated to correct errors of measures related to each country-specific questionnaire. Associations between proteins (total, animal, and vegetable) or food sources of animal proteins, and IBD risk were estimated by Cox proportional hazard models.After a mean follow-up of 16 years, 177 patients with Crohn's disease (CD) and 418 with ulcerative colitis (UC), were identified. There was no association between total protein, animal, or vegetable protein intakes and CD or UC risks. Total meat and red meat intakes were associated with UC risk (HR for the 4 thvs. 1 st quartile = 1.40; 95% CI = 0.99-1.98; P-trend = 0.01; and 1.61; 95% CI = 1.10-2.36, P-trend = 0.007, respectively). There was no association between other food sources of animal protein (processed meat, fish, shellfish, eggs, poultry) and UC. We found no association between food sources of animal proteins and CD risk.Meat and red meat consumptions are associated with higher risks of UC. These results support dietary counseling of low meat intake in people at high-risk of IBD.

Keyword(s): Diet ; inflammatory bowel disease ; meat

Note: 2022 Aug 30;16(8):1187-1196

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Contributing Institute(s):

1. C020 Epidemiologie von Krebs (C020)

Research Program(s):

1. 313 - Krebsrisikofaktoren und Prävention (POF4-313) (POF4-313)

Appears in the scientific report 2022

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Database coverage:
; Clarivate Analytics Master Journal List ; Current Contents - Clinical Medicine ; Ebsco Academic Search ; Essential Science Indicators ; IF >= 10 ; JCR ; Nationallizenz ; SCOPUS ; Science Citation Index Expanded ; Web of Science Core Collection

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