Journal Article DKFZ-2023-01589

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The winner takes it all: Competition drives clonal selection in gliomagenesis.



2023
Elsevier New York, NY

Cancer cell 41(8), 1394–1396 () [10.1016/j.ccell.2023.07.003]
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Abstract: The exact mechanisms that govern clonal dynamics and selection during early tumorigenesis remain largely elusive. Ceresa et al. provide experimental and mathematical evidence that MYC-dependent competition between individual clones is one driving force of brain tumor evolution, adding a winner/loser aspect to the picture that complements existing concepts.

Classification:

Note: #LA:B320# / 41(8), pp. 1394–1396 / Note

Contributing Institute(s):
  1. KKE Neuroonkologie (B320)
  2. DKTK HD zentral (HD01)
Research Program(s):
  1. 312 - Funktionelle und strukturelle Genomforschung (POF4-312) (POF4-312)

Appears in the scientific report 2023
Database coverage:
Medline ; BIOSIS Previews ; Biological Abstracts ; Clarivate Analytics Master Journal List ; Current Contents - Clinical Medicine ; Current Contents - Life Sciences ; Ebsco Academic Search ; Essential Science Indicators ; IF >= 50 ; JCR ; SCOPUS ; Science Citation Index Expanded ; Web of Science Core Collection
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 Record created 2023-08-07, last modified 2024-02-29



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