Journal Article

DKFZ-2024-00008

http://join2-wiki.gsi.de/foswiki/pub/Main/Artwork/join2_logo100x88.png Survival in oral and pharyngeal cancers is catching up with laryngeal cancer in the NORDIC countries through a half century.

Zitricky, F. ; Koskinen, A. I. ; Hemminki, O. ; Försti, A.DKFZ* ; Hemminki, A. ; Hemminki, K. (Last author)DKFZ*

2024
Wiley Hoboken, NJ

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Please use a persistent id in citations: doi:10.1002/cam4.6867

Abstract: Cancers of the head and neck (HN) are heterogeneous tumors with incidence rates varying globally. In Northern Europe oral and oropharyngeal cancers are the most common individual types. Survival for HN varies by individual tumor type but for most of them survival trends are not well known over extended periods of time.Data for a retrospective survival study were obtained for Danish, Finnish, Norwegian, and Swedish patients from the NORDCAN database from 1971 to 2020. Relative 1- and 5-year survival rates and 5/1-year conditional survival for years 2-5 were calculated.Both 1- and 5-year survival improved for all HN cancers but only marginally for laryngeal cancer. For the other cancers a 50-year increase in 5-year survival was about 30% units for nasopharyngeal and oropharyngeal cancers, 20% units for oral cancer and somewhat less for hypopharyngeal cancer.5-year survival reached about 65% for all HN cancers, except for hypopharyngeal cancer (30%). Human papilloma virus infection is becoming a dominant risk factor for the rapidly increasing oropharyngeal cancer, the prevention of which needs to emphasize oral sex as a route of infection.

Keyword(s): conditional survival ; human papilloma virus ; oral cancer ; pharyngeal cancer

Note: #LA:Z999# / 2024 Jan 2;13(1):e6867

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Contributing Institute(s):

1. B062 Pädiatrische Neuroonkologie (B062)
2. DKTK HD zentral (HD01)
3. Erimitus im DKFZ (Z999)

Research Program(s):

1. 313 - Krebsrisikofaktoren und Prävention (POF4-313) (POF4-313)

Appears in the scientific report 2024

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