Journal Article (Review Article)

DKFZ-2024-01546

http://join2-wiki.gsi.de/foswiki/pub/Main/Artwork/join2_logo100x88.png SNO-EANO-EURACAN consensus on management of pineal parenchymal tumors.

Liu, A. P. Y. ; Li, B. K. ; Vasiljevic, A. ; Dewan, M. C. ; Tamrazi, B. ; Ertl-Wagner, B. ; Hansford, J. R. ; Pfaff, E.DKFZ* ; Mynarek, M. ; Ng, H.-K. ; Tsang, D. S. ; Gottardo, N. G. ; Gajjar, A. ; Bouffet, E. ; Dufour, C. ; Pizer, B. ; Schiff, D. ; Jenkinson, M. D. ; Lombardi, G. ; Wen, P. Y. ; van den Bent, M. J. ; Huang, A.

2024
Oxford Univ. Press Oxford

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Please use a persistent id in citations: doi:10.1093/neuonc/noae128

Abstract: Pineal parenchymal tumors are rare neoplasms for which evidence-based treatment recommendations are lacking. These tumors vary in biology, clinical characteristics, and prognosis, requiring treatment that ranges from surgical resection alone to intensive multimodal antineoplastic therapy. Recently, international collaborative studies have shed light on the genomic landscape of these tumors, leading to refinement in molecular-based disease classification in the 5th edition of the World Health Organization (WHO) classification of tumors of the central nervous system. In this review, we summarize the literature on diagnostic and therapeutic approaches, and suggest pragmatic recommendations for the clinical management of patients presenting with intrinsic pineal region masses including parenchymal tumors (pineocytoma, pineal parenchymal tumor of intermediate differentiation, and pineoblastoma), pineal cyst, and papillary tumors of the pineal region.

Keyword(s): clinical treatment guidelines ; papillary tumor of pineal region ; pineal cyst ; pineal parenchymal tumors ; risk-stratification

Note: 2024 Dec 5;26(12):2159-2173

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Contributing Institute(s):

1. Pädiatrische Gliomforschung (B360)

Research Program(s):

1. 312 - Funktionelle und strukturelle Genomforschung (POF4-312) (POF4-312)

Appears in the scientific report 2024

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Database coverage:
; Clarivate Analytics Master Journal List ; Current Contents - Clinical Medicine ; Essential Science Indicators ; IF >= 15 ; JCR ; Nationallizenz ; PubMed Central ; SCOPUS ; Science Citation Index Expanded ; Web of Science Core Collection

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