Journal Article DKFZ-2025-02234

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A Monte Carlo dose engine for fast neutron therapy and boron neutron capture therapy for matRad.

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2025
IOP Publ. Bristol

Biomedical physics & engineering express 11(6), 065023 () [10.1088/2057-1976/ae12f7]
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Abstract: Objective:The purpose of the work presented here was to enable easy access to Monte Carlo dose calculation for both fast neutron therapy and boron neutron capture therapy for research purposes. The dose calculation approach was especially intended to hold high customization potential for individual user applications.Approach:The dose engine is based on the Monte Carlo code MCNP. It is integrated into the MATLAB-based open source research treatment planning software matRad as modular component.Main results:Total dose calculation is enabled for both fast neutron therapy and boron neutron capture therapy on patient CT data. The evaluation of the dose distribution is possible using the matRad graphical user interface and dose volume histograms. Customization options are provided for advanced users.Significance:The open source treatment planning software allows easy access to highly accurate Monte Carlo dose calculation for research projects.

Keyword(s): Monte Carlo Method (MeSH) ; Boron Neutron Capture Therapy: methods (MeSH) ; Humans (MeSH) ; Radiotherapy Planning, Computer-Assisted: methods (MeSH) ; Software (MeSH) ; Radiotherapy Dosage (MeSH) ; Computer Simulation (MeSH) ; Fast Neutrons: therapeutic use (MeSH) ; Algorithms (MeSH) ; MCNP dose calculation ; Monte Carlo dose calculation ; boron neutron capture therapy ; fast fission neutron therapy ; fission neutron source ; neutron dose calculation

Classification:

Contributing Institute(s):
  1. E040 Med. Physik in der Strahlentherapie (E040)
Research Program(s):
  1. 315 - Bildgebung und Radioonkologie (POF4-315) (POF4-315)

Appears in the scientific report 2025
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Medline ; Clarivate Analytics Master Journal List ; Emerging Sources Citation Index ; IF < 5 ; JCR ; National-Konsortium ; SCOPUS ; Web of Science Core Collection
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 Record created 2025-10-30, last modified 2025-10-31



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