Journal Article

DKFZ-2025-02572

http://join2-wiki.gsi.de/foswiki/pub/Main/Artwork/join2_logo100x88.png You (bacteria) shall not pass: NLRP6 can sense you!

Weber, A.DKFZ* ; Rosenstiel, P.

2025
Nature Publishing Group UK [London]

Abstract: The ability of intracellular bacteria to spread directly from one cell to the next, avoiding extracellular immune defenses and drugs, is essential for pathogen dissemination and, ultimately, the progression and severity of infection. In this issue of The EMBO Journal, Boegli and colleagues uncover a previously unrecognized role of the enigmatic innate immune sensor NLRP6 in detecting bacteria-induced lysosomal damage and triggering cytokine release or cell death to limit infection.

Note: epub

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Contributing Institute(s):

1. DKTK Koordinierungsstelle Tübingen (TU01)

Research Program(s):

1. 899 - ohne Topic (POF4-899) (POF4-899)

Appears in the scientific report 2025

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Database coverage:
; ; ; Article Processing Charges ; BIOSIS Previews ; Biological Abstracts ; Clarivate Analytics Master Journal List ; Current Contents - Life Sciences ; DEAL Wiley ; DOAJ Seal ; Ebsco Academic Search ; Essential Science Indicators ; Fees ; IF >= 10 ; JCR ; SCOPUS ; Science Citation Index Expanded ; Web of Science Core Collection

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