Journal Article (Review Article) DKFZ-2026-00899

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The current landscape of therapeutic vaccination approaches for treatment of HPV-dependent malignancies.

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2026
Nature Publishing Group [London]

npj vaccines 11, 89 () [10.1038/s41541-026-01426-8]
 GO

Abstract: This review provides an overview of current therapeutic human papillomavirus (HPV) vaccination approaches. We review important criteria for their development, and present vaccines currently being actively followed in clinical trials, for precursor lesions or established cancers. Subsequently, we list approaches that reached clinical trial stage but were abandoned. Lastly, we discuss promising preclinical studies. We conclude with a brief overview of novel in silico tools developed to enhance vaccine design.

Classification:

Note: #EA:D410#LA:D410# / 11, Article number: 89 (2026)

Contributing Institute(s):
  1. Immuntherapie und -prävention (D410)
Research Program(s):
  1. 314 - Immunologie und Krebs (POF4-314) (POF4-314)

Appears in the scientific report 2026
Database coverage:
Medline ; Creative Commons Attribution CC BY (No Version) ; DOAJ ; OpenAccess ; Article Processing Charges ; BIOSIS Previews ; Biological Abstracts ; Clarivate Analytics Master Journal List ; DOAJ Seal ; Essential Science Indicators ; Fees ; SCOPUS ; Science Citation Index Expanded ; Web of Science Core Collection
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 Record created 2026-04-17, last modified 2026-06-03


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