B087
B087 Neuroblastom Genomik
ID | I:(DE-He78)B087-20160331 |
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Journal Article
Herter, S. (First author)DKFZ* ; Emperador, M.DKFZ* ; Smyrilli, K.DKFZ* ; Kocher, D.DKFZ* ; Celikyürekli, S.DKFZ* ; Zeiser, C.DKFZ* ; Gerloff, X.DKFZ* ; Kreth, S.DKFZ* ; Henrich, K.-O.DKFZ* ; Maaß, K. K.DKFZ* ; Rettenmeier, J.DKFZ* ; Grünewald, T.DKFZ* ; Peterziel, H.DKFZ* ; Westermann, F.DKFZ* ; Hamacher-Brady, A. ; Witt, O.DKFZ* ; Oehme, I. (Last author)DKFZ*
High content-imaging drug synergy screening identifies specific senescence-related vulnerabilities of mesenchymal neuroblastomas.
Cell death & disease 16(1), 644 (2025) [10.1038/s41419-025-07933-1]2025
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Journal Article
Penzo, C. ; Özel, I.DKFZ* ; Martinovic, M. ; Kuzman, M. ; Glavas, D. ; Stanic, M. ; Reichenbach, T. ; Müller, T. G. ; Rheinberger, M. ; Godarzi, N. ; Lapaillerie, D. ; Srezovic, B. ; dell'Oca, M. C. ; Lange, L. C. ; Sadhu, L. ; de Castro, I. J. ; Shytaj, I. L. ; Forcato, M. ; Laketa, V. ; Bicciato, S. ; Vlahovicek, K. ; Fackler, O. T. ; Lucic, B. ; Pena, V. ; Kräusslich, H.-G. ; Parissi, V. ; Lusic, M.
Aquarius helicase facilitates HIV-1 integration into R-loop enriched genomic regions.
Nature microbiology 10(9), 2306-2322 (2025) [10.1038/s41564-025-02089-2]2025
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Journal Article (Review Article)
DuBois, S. G. ; Moreno, L. ; Anderson, J. ; Asgharzadeh, S. ; Bagatell, R. ; Beck-Popovic, M. ; Belle, J. ; Berlanga, P. ; Bird, N. J. ; Chesler, L. ; Durbin, A. ; Eggert, A. ; Eilers, M. ; Federico, S. M. ; Fischer, M. ; Gatz, S. A. ; George, R. E. ; George, S. ; Goldsmith, K. C. ; Gray, J. ; Heczey, A. ; Irwin, M. S. ; Knox, L. ; Lode, H. N. ; Ludwinski, D. ; Macy, M. E. ; Majzner, R. G. ; Maris, J. M. ; Modak, S. ; Molenaar, J. J. ; Morgenstern, D. A. ; Mossé, Y. P. ; Owens, C. ; Reynolds, C. P. ; Rossig, C. ; Schleiermacher, G. ; Scott, L. ; Sondel, P. M. ; Speleman, F. ; van Noesel, M. ; Westermann, F.DKFZ* ; Wienke, J. ; Wolpaw, A. J. ; Park, J. R. ; Pearson, A. D. J.
Accelerating Drug Development for Neuroblastoma: Consensus Statement From the Third Neuroblastoma Drug Development Strategy Forum.
Pediatric blood & cancer 72(9), e31831 (2025) [10.1002/pbc.31831]2025
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Journal Article
Okonechnikov, K. (First author)DKFZ* ; Joshi, P. K. (First author)DKFZ* ; Körber, V. (First author)DKFZ* ; Rademacher, A.DKFZ* ; Bortolomeazzi, M.DKFZ* ; Mallm, J.-P.DKFZ* ; Vaillant, J.DKFZ* ; da Silva, P. B. G.DKFZ* ; Statz, B.DKFZ* ; Sepp, M. ; Sarropoulos, I. ; Yamada, T. ; Wittmann, A.DKFZ* ; Schramm, K.DKFZ* ; Blattner-Johnson, M.DKFZ* ; Fiesel, P.DKFZ* ; Jones, B.DKFZ* ; Jäger, N.DKFZ* ; Milde, T.DKFZ* ; Pajtler, K.DKFZ* ; van Tilburg, C. M.DKFZ* ; Witt, O.DKFZ* ; Bochennek, K. ; Weber, K. J.DKFZ* ; Nonnenmacher, L. ; Reimann, C. ; Ghasemi, D. R.DKFZ* ; Schüller, U. ; Mynarek, M. ; Rutkowski, S. ; Jones, D.DKFZ* ; Korshunov, A.DKFZ* ; Rippe, K.DKFZ* ; Westermann, F.DKFZ* ; Thongjuea, S.DKFZ* ; Höfer, T.DKFZ* ; Kaessmann, H.DKFZ* ; Kutscher, L. (Last author)DKFZ* ; Pfister, S. (Last author)DKFZ*
Oncogene aberrations drive medulloblastoma progression, not initiation.
Nature 642(8069), 1062-1072 (2025) [10.1038/s41586-025-08973-5]2025
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Journal Article
Sollier, E. (First author)DKFZ* ; Riedel, A. (First author)DKFZ* ; Toprak, U. (First author)DKFZ* ; et al
Enhancer hijacking discovery in acute myeloid leukemia by pyjacker identifies MNX1 activation via deletion 7q.
Blood cancer discovery 6(4), 343-363 (2025) [10.1158/2643-3230.BCD-24-0278]2025
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Journal Article
Grunewald, L.DKFZ* ; Andersch, L.DKFZ* ; Helmsauer, K. ; Schwiebert, S. ; Klaus, A. ; Henssen, A. G. ; Straka, T. ; Lodrini, M. ; Wicha, S. G. ; Fuchs, S.DKFZ* ; Hertwig, F. ; Westermann, F.DKFZ* ; Vitali, A. ; Caramel, C. ; Büchel, G. ; Eilers, M. ; Astrahantseff, K. ; Eggert, A.DKFZ* ; Höpken, U. E. ; Schulte, J. H. ; Blankenstein, T. ; Anders, K. ; Künkele, A.DKFZ*
Targeting MYCN upregulates L1CAM tumor antigen in MYCN-dysregulated neuroblastoma to increase CAR T cell efficacy.
Pharmacological research 212, 107608 (2025) [10.1016/j.phrs.2025.107608]2025
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Journal Article (Review Article)
Avinent-Pérez, M. (First author)DKFZ* ; Westermann, F.DKFZ* ; Navarro, S. ; López-Carrasco, A. ; Noguera, R.
Tackling ALT-positive neuroblastoma: is it time to redefine risk classification systems? A systematic review with IPD meta-analysis.
Neoplasia 60, 101106 (2025) [10.1016/j.neo.2024.101106]2025
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Preprint
Okonechnikov, K. (First author)DKFZ* ; Joshi, P. K.DKFZ* ; Körber, V.DKFZ* ; Rademacher, A.DKFZ* ; Bortolomeazzi, M.DKFZ* ; Mallm, J.-P.DKFZ* ; da Silva, P. B. G.DKFZ* ; Statz, B.DKFZ* ; Sepp, M. ; Sarropoulos, I. ; Yamada-Saito, T. ; Vaillant, J.DKFZ* ; Wittmann, A.DKFZ* ; Schramm, K.DKFZ* ; Blattner-Johnson, M.DKFZ* ; Fiesel, P.DKFZ* ; Jones, B.DKFZ* ; Milde, T.DKFZ* ; Pajtler, K.DKFZ* ; van Tilburg, C. M.DKFZ* ; Witt, O.DKFZ* ; Bochennek, K. ; Weber, K. J. ; Nonnenmacher, L. ; Reimann, C. ; Schüller, U. ; Mynarek, M. ; Rutkowski, S. ; Jones, D. T. W.DKFZ* ; Korshunov, A.DKFZ* ; Rippe, K.DKFZ* ; Westermann, F.DKFZ* ; Thongjuea, S.DKFZ* ; Höfer, T.DKFZ* ; Kaessmann, H. ; Kutscher, L.DKFZ* ; Pfister, S. (Last author)DKFZ*
Medulloblastoma oncogene aberrations are not involved in tumor initiation, but essential for disease progression and therapy resistance
[doi.org/10.1101/2024.02.09.579690]
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Journal Article
Weichenhan, D. (First author)DKFZ* ; Riedel, A. (First author)DKFZ* ; Sollier, E. (First author)DKFZ* ; Toprak, U. (First author)DKFZ* ; Hey, J.DKFZ* ; Breuer, K.DKFZ* ; Wierzbinska, J. A.DKFZ* ; Touzart, A.DKFZ* ; Lutsik, P.DKFZ* ; Bähr, M.DKFZ* ; Östlund, A. ; Nilsson, T. ; Jacobsson, S. ; Waraky, A. ; Behrens, Y. L. ; Göhring, G. ; Schlegelberger, B. ; Steinek, C. ; Harz, H. ; Leonhardt, H. ; Dolnik, A. ; Reinhardt, D. ; Bullinger, L. ; Palmqvist, L. ; Lipka, D. (Last author)DKFZ* ; Plass, C. (Last author)DKFZ*
Altered enhancer-promoter interaction leads to MNX1 expression in pediatric acute myeloid leukemia with t(7;12)(q36;p13).
Blood advances 8(19), 5100-5111 (2024) [10.1182/bloodadvances.2023012161]2024
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Journal Article
Seiboldt, T. (First author)DKFZ* ; Zeiser, C.DKFZ* ; Nguyen, D.DKFZ* ; Celikyürekli, S.DKFZ* ; Herter, S.DKFZ* ; Najafi, S.DKFZ* ; Stroh-Dege, A.DKFZ* ; Meulenbroeks, C. ; Mack, N.DKFZ* ; Salem-Altintas, R.DKFZ* ; Westermann, F.DKFZ* ; Schlesner, M.DKFZ* ; Milde, T.DKFZ* ; Kool, M.DKFZ* ; Holland-Letz, T.DKFZ* ; Vogler, M.DKFZ* ; Peterziel, H.DKFZ* ; Witt, O.DKFZ* ; Oehme, I. (Last author)DKFZ*
Synergy of retinoic acid and BH3 mimetics in MYC(N)-driven embryonal nervous system tumours.
British journal of cancer 131(4), 763-777 (2024) [10.1038/s41416-024-02740-5]2024
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All known publications ...
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