W120
Proteomics
Also known as:Helm; Proteinanalyse; W120
ID | I:(DE-He78)W120-20160331 |
Recent Publications
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Journal Article
Umbaugh, C. S. (First author)DKFZ* ; Groth, M. (First author)DKFZ* ; Erkut, C.DKFZ* ; Lee, K.DKFZ* ; Marinho, J. ; Linder, S.DKFZ* ; Iser, F.DKFZ* ; Kapp, J.DKFZ* ; Schroeter, P.DKFZ* ; Dolaner, S.DKFZ* ; Kayserili, A.DKFZ* ; Helm, D.DKFZ* ; Schneider, M.DKFZ* ; Hartmann, J.DKFZ* ; Walch, P.DKFZ* ; Barth, T. F. E. ; Mellert, K. ; Dreier, B. ; Schaefer, J. V. ; Plückthun, A. ; Fröhling, S. (Last author)DKFZ* ; Scholl, C. (Last author)DKFZ*
Selective targeting of TBXT with DARPins identifies regulatory networks and therapeutic vulnerabilities in chordoma.
Science advances 11(36), eadu2796 (2025) [10.1126/sciadv.adu2796]2025
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Teibo, J. O. ; Silveira, R. M. ; Silvestrini, V. C. ; Archiolli, I. ; PaulaMasson, A. ; de Morais, B. P. ; Schmidt, D. ; Dos Santos, M. H. ; Ferreira, G. A. ; Thomé, C. H. ; Helm, D.DKFZ* ; Nirujogi, R. S. ; Alessi, D. R. ; Picanço-Castro, V. ; de Souza, L. E. B. ; Faça, V. M.
Proteomics analysis reveals early event molecular effectors of anti-CD19 CAR-T cell therapy in hematological cancer.
Journal of proteomics 321, 105507 (2025) [10.1016/j.jprot.2025.105507]2025
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Rios de los Rios Resendiz, J. (First author)DKFZ* ; Herrmann-Sim, F.DKFZ* ; Wilkesmann, L.DKFZ* ; Helm, D.DKFZ* ; Schneider, M.DKFZ* ; Campione, G.DKFZ* ; Plügge, K.DKFZ* ; Greiner, G.DKFZ* ; Lazaro Garcia, L.DKFZ* ; Berker, J.DKFZ* ; Richter, K.DKFZ* ; Zielske, L.DKFZ* ; Hofmann, W.-K. ; Clemm von Hohenberg, K. (Last author)DKFZ*
A translational protocol optimizes the isolation of plasma-derived extracellular vesicle proteomics.
Scientific reports 15(1), 24292 (2025) [10.1038/s41598-025-08366-8]2025
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Daum, A.-K. (First author)DKFZ* ; Schlicker, L.DKFZ* ; Schneider, M. A. ; Muley, T. ; Klingmüller, U.DKFZ* ; Schulze, A.DKFZ* ; Thomas, M. ; Christopoulos, P. ; Sültmann, H. (Last author)DKFZ*
Cancer-associated fibroblasts promote drug resistance in ALK-driven lung adenocarcinoma cells by upregulating lipid biosynthesis.
Cancer & metabolism 13(1), 28 (2025) [10.1186/s40170-025-00400-7]2025
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Hermann, J. (First author)DKFZ* ; Bortecen, T.DKFZ* ; Kalis, R. ; Kowar, A.DKFZ* ; Pechincha, C.DKFZ* ; Vogt, V. ; Schneider, M.DKFZ* ; Helm, D.DKFZ* ; Krijgsveld, J.DKFZ* ; Loayza-Puch, F.DKFZ* ; Zuber, J. ; Palm, W. (Last author)DKFZ*
mTORC1 cooperates with tRNA wobble modification to sustain the protein synthesis machinery.
Nature Communications 16(1), 4201 (2025) [10.1038/s41467-025-59185-4]2025
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Rajagopal, V. (First author)DKFZ* ; Seiler, J. S. (First author)DKFZ* ; Nasa, I. ; Cantarella, S.DKFZ* ; Theiss, J.DKFZ* ; Herget, F.DKFZ* ; Kaifer, B.DKFZ* ; Klostermann, M. ; Will, R.DKFZ* ; Schneider, M.DKFZ* ; Helm, D.DKFZ* ; König, J. ; Zarnack, K. ; Diederichs, S.DKFZ* ; Kettenbach, A. N. ; Caudron-Herger, M. (Last author)DKFZ*
An atlas of RNA-dependent proteins in cell division reveals the riboregulation of mitotic protein-protein interactions.
Nature Communications 16(1), 2325 (2025) [10.1038/s41467-025-57671-3]2025
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Journal Article (Letter)
Cheytan, T. (First author)DKFZ* ; Schneider, M.DKFZ* ; Würth, R.DKFZ* ; Schwerd-Kleine, P.DKFZ* ; Gutjahr, E.DKFZ* ; Thewes, V.DKFZ* ; Michel, L. L. ; Weber, R.DKFZ* ; Vorberg, T.DKFZ* ; Lohr, S.DKFZ* ; Nitschke, K. ; Neßling, M.DKFZ* ; Lichter, P.DKFZ* ; Schneeweiss, A. ; Richter, K.DKFZ* ; Helm, D.DKFZ* ; Sprick, M.DKFZ* ; Trumpp, A. (Last author)DKFZ*
Small extracellular vesicles and particles (sEVPs) derived from tumor-free pre-metastatic organs promote breast cancer metastasis and support organotropism.
Molecular cancer 24(1), 72 (2025) [10.1186/s12943-025-02235-8]2025
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Journal Article
Lim, B. (First author)DKFZ* ; Kamal, A. ; Gomez Ramos, B.DKFZ* ; Adrian Segarra, J.DKFZ* ; Ibarra, I. L. ; Dignas, L.DKFZ* ; Kindinger, T.DKFZ* ; Volz, K.DKFZ* ; Rahbari, M.DKFZ* ; Rahbari, N. ; Poisel, E.DKFZ* ; Kafetzopoulou, K.DKFZ* ; Böse, L.DKFZ* ; Breinig, M.DKFZ* ; Heide, D.DKFZ* ; Gallage, S. U.DKFZ* ; Barragan Avila, J. E.DKFZ* ; Wiethoff, H. ; Berest, I. ; Schnabellehner, S. ; Schneider, M.DKFZ* ; Becker, J.DKFZ* ; Helm, D.DKFZ* ; Grimm, D. ; Mäkinen, T. ; Tschaharganeh, D. F.DKFZ* ; Heikenwalder, M.DKFZ* ; Zaugg, J. B. ; Mall, M. (Last author)DKFZ*
Active repression of cell fate plasticity by PROX1 safeguards hepatocyte identity and prevents liver tumorigenesis.
Nature genetics 57(3), 668-679 (2025) [10.1038/s41588-025-02081-w]2025
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Journal Article
Sumer, O. E. (First author)DKFZ* ; Schelzig, K. (First author)DKFZ* ; Jung, J.DKFZ* ; Li, X.DKFZ* ; Moros, J.DKFZ* ; Schwarzmüller, L.DKFZ* ; Sen, E.DKFZ* ; Karolus, S.DKFZ* ; Wörner, A.DKFZ* ; de Melo Costa, V. R.DKFZ* ; Nataraj, N. B. ; Vlachavas, E.-I.DKFZ* ; Gerhäuser, C.DKFZ* ; Müller-Decker, K.DKFZ* ; Helm, D.DKFZ* ; Yarden, Y. ; Michels, B. E.DKFZ* ; Körner, C. (Last author)DKFZ*
Selective arm-usage of pre-miR-1307 dysregulates angiogenesis and affects breast cancer aggressiveness.
BMC biology 23(1), 25 (2025) [10.1186/s12915-025-02133-x]2025
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Journal Article (Letter)
Jin, J. X. (First author)DKFZ* ; Fuchslocher, F.DKFZ* ; Carreno-Gonzalez, M.DKFZ* ; Zahnow, F.DKFZ* ; Ceranski, A. K.DKFZ* ; Will, R.DKFZ* ; Helm, D.DKFZ* ; Bestvater, F.DKFZ* ; Banito, A.DKFZ* ; Imle, R.DKFZ* ; Ohmura, S.DKFZ* ; Cidre-Aranaz, F.DKFZ* ; Grünewald, T. (Last author)DKFZ*
Loss of SMARCB1 evokes targetable epigenetic vulnerabilities in epithelioid sarcoma.
Cancer communications 45(5), 494-499 (2025) [10.1002/cac2.12665]2025
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All known publications ...
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