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Recent Publications

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http://join2-wiki.gsi.de/foswiki/pub/Main/Artwork/join2_logo100x88.png Journal Article Walzik, D. ; Joisten, N. ; Metcalfe, A. J. ; Proschinger, S. ; Schenk, A. ; Wenzel, C. ; Henneberg, A.DKFZ* ; Schneider, M.DKFZ* ; Calderazzo, S.DKFZ* ; Groll, A. ; Watzl, C. ; Opitz, C.DKFZ* ; Helm, D.DKFZ* ; Zimmer, P.
Acute exercise rewires the proteomic landscape of human immune cells.
Nature Communications nn, nn (2026) [10.1038/s41467-025-68101-9]2026   BibTeX | EndNote: XML, Text | RIS

http://join2-wiki.gsi.de/foswiki/pub/Main/Artwork/join2_logo100x88.png Journal Article Distler, U. ; Yoo, H. B. ; Kardell, O. ; Hein, D. ; Sielaff, M. ; Scherer, M. ; Jozefowicz, A. M. ; Leps, C. ; Gómez-Zepeda, D.DKFZ* ; von Toerne, C. ; Merl-Pham, J. ; Barth, T. K. ; Tüshaus, J. ; Giesbertz, P. ; Müller, T.DKFZ* ; Kliewer, G.DKFZ* ; Aljakouch, K.DKFZ* ; Helm, B.DKFZ* ; Unger, H.DKFZ* ; Frey, D.DKFZ* ; Helm, D.DKFZ* ; Schwarzmüller, L.DKFZ* ; Popp, O. ; Qin, D. ; Wudy, S. I. ; Sinn, L. R. ; Mergner, J. ; Ludwig, C. ; Imhof, A. ; Kuster, B. ; Lichtenthaler, S. F. ; Krijgsveld, J.DKFZ* ; Klingmüller, U.DKFZ* ; Mertins, P. ; Coscia, F. ; Ralser, M. ; Mülleder, M. ; Hauck, S. M. ; Tenzer, S. (Last author)DKFZ*
Multicenter evaluation of label-free quantification in human plasma on a high dynamic range benchmark set.
Nature Communications 16(1), 8774 (2025) [10.1038/s41467-025-64501-z]2025     Fulltext by Pubmed Central BibTeX | EndNote: XML, Text | RIS

http://join2-wiki.gsi.de/foswiki/pub/Main/Artwork/join2_logo100x88.png Journal Article Umbaugh, C. S. (First author)DKFZ* ; Groth, M. (First author)DKFZ* ; Erkut, C.DKFZ* ; Lee, K.DKFZ* ; Marinho, J. ; Linder, S.DKFZ* ; Iser, F.DKFZ* ; Kapp, J.DKFZ* ; Schroeter, P.DKFZ* ; Dolaner, S.DKFZ* ; Kayserili, A.DKFZ* ; Helm, D.DKFZ* ; Schneider, M.DKFZ* ; Hartmann, J.DKFZ* ; Walch, P.DKFZ* ; Barth, T. F. E. ; Mellert, K. ; Dreier, B. ; Schaefer, J. V. ; Plückthun, A. ; Fröhling, S. (Last author)DKFZ* ; Scholl, C. (Last author)DKFZ*
Selective targeting of TBXT with DARPins identifies regulatory networks and therapeutic vulnerabilities in chordoma.
Science advances 11(36), eadu2796 (2025) [10.1126/sciadv.adu2796]2025   BibTeX | EndNote: XML, Text | RIS

http://join2-wiki.gsi.de/foswiki/pub/Main/Artwork/join2_logo100x88.png Journal Article Teibo, J. O. ; Silveira, R. M. ; Silvestrini, V. C. ; Archiolli, I. ; PaulaMasson, A. ; de Morais, B. P. ; Schmidt, D. ; Dos Santos, M. H. ; Ferreira, G. A. ; Thomé, C. H. ; Helm, D.DKFZ* ; Nirujogi, R. S. ; Alessi, D. R. ; Picanço-Castro, V. ; de Souza, L. E. B. ; Faça, V. M.
Proteomics analysis reveals early event molecular effectors of anti-CD19 CAR-T cell therapy in hematological cancer.
Journal of proteomics 321, 105507 (2025) [10.1016/j.jprot.2025.105507]2025   BibTeX | EndNote: XML, Text | RIS

http://join2-wiki.gsi.de/foswiki/pub/Main/Artwork/join2_logo100x88.png Journal Article Rios de los Rios Resendiz, J. (First author)DKFZ* ; Herrmann-Sim, F.DKFZ* ; Wilkesmann, L.DKFZ* ; Helm, D.DKFZ* ; Schneider, M.DKFZ* ; Campione, G.DKFZ* ; Plügge, K.DKFZ* ; Greiner, G.DKFZ* ; Lazaro Garcia, L.DKFZ* ; Berker, J.DKFZ* ; Richter, K.DKFZ* ; Zielske, L.DKFZ* ; Hofmann, W.-K. ; Clemm von Hohenberg, K. (Last author)DKFZ*
A translational protocol optimizes the isolation of plasma-derived extracellular vesicle proteomics.
Scientific reports 15(1), 24292 (2025) [10.1038/s41598-025-08366-8]2025     Fulltext by Pubmed Central BibTeX | EndNote: XML, Text | RIS

http://join2-wiki.gsi.de/foswiki/pub/Main/Artwork/join2_logo100x88.png Journal Article Daum, A.-K. (First author)DKFZ* ; Schlicker, L.DKFZ* ; Schneider, M. A. ; Muley, T. ; Klingmüller, U.DKFZ* ; Schulze, A.DKFZ* ; Thomas, M. ; Christopoulos, P. ; Sültmann, H. (Last author)DKFZ*
Cancer-associated fibroblasts promote drug resistance in ALK-driven lung adenocarcinoma cells by upregulating lipid biosynthesis.
Cancer & metabolism 13(1), 28 (2025) [10.1186/s40170-025-00400-7]2025     Fulltext by Pubmed Central BibTeX | EndNote: XML, Text | RIS

http://join2-wiki.gsi.de/foswiki/pub/Main/Artwork/join2_logo100x88.png Journal Article Hermann, J. (First author)DKFZ* ; Bortecen, T.DKFZ* ; Kalis, R. ; Kowar, A.DKFZ* ; Pechincha, C.DKFZ* ; Vogt, V. ; Schneider, M.DKFZ* ; Helm, D.DKFZ* ; Krijgsveld, J.DKFZ* ; Loayza-Puch, F.DKFZ* ; Zuber, J. ; Palm, W. (Last author)DKFZ*
mTORC1 cooperates with tRNA wobble modification to sustain the protein synthesis machinery.
Nature Communications 16(1), 4201 (2025) [10.1038/s41467-025-59185-4]2025     Fulltext by Pubmed Central BibTeX | EndNote: XML, Text | RIS

http://join2-wiki.gsi.de/foswiki/pub/Main/Artwork/join2_logo100x88.png Journal Article Frey, D. (First author)DKFZ* ; Helm, B.DKFZ* ; Guerra, M. ; Hagner, M. ; Lu, J. ; Dittrich, A. S. ; Wege, S. ; Eberhardt, R. ; Herth, F. J. F. ; Sommerburg, O. ; Schultz, C. ; Dalpke, A. H. ; Klingmüller, U. (Last author)DKFZ* ; Mall, M. A. ; Boutin, S.
SputOMICs identifies common and distinct markers in cystic fibrosis and chronic obstructive pulmonary disease.
Scientific reports 15(1), 44418 (2025) [10.1038/s41598-025-32565-y]2025     Fulltext by Pubmed Central BibTeX | EndNote: XML, Text | RIS

http://join2-wiki.gsi.de/foswiki/pub/Main/Artwork/join2_logo100x88.png Preprint Schwarzmüller, L. (First author)DKFZ* ; Müller, J.DKFZ* ; Vlachavas, E.-I.DKFZ* ; Beumers, L.DKFZ* ; Fleischhacker, L.DKFZ* ; Burmester, S.DKFZ* ; Helm, D.DKFZ* ; Körner, C.DKFZ* ; Wiemann, S. (Last author)DKFZ*
PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and Tamoxifen in a luminal A breast cancer model
[doi.org/10.1101/2025.04.28.651009]   BibTeX | EndNote: XML, Text | RIS

http://join2-wiki.gsi.de/foswiki/pub/Main/Artwork/join2_logo100x88.png Journal Article Simon, N. (First author)DKFZ* ; Volz, S.DKFZ* ; Rios de los Rios Reséndiz, J.DKFZ* ; Wedig, T.DKFZ* ; Montigel, S. H.DKFZ* ; Schwarz, N.DKFZ* ; Richter, K.DKFZ* ; Helm, D.DKFZ* ; Neßling, M.DKFZ* ; Zielske, L.DKFZ* ; Berker, J.DKFZ* ; Russeck, S.DKFZ* ; Mauermann, M.DKFZ* ; Hofmann, W.-K. ; Pfister, S. M.DKFZ* ; Pajtler, K. W.DKFZ* ; Maaß, K. K.DKFZ* ; Clemm von Hohenberg, K. (Last author)DKFZ*
Preanalytical framework for routine clinical use of liquid biopsies: combining EVs and cfDNA
Extracellular vesicles and circulating nucleic acids 6, 626 - 650 (2025) [10.20517/evcna.2025.44]2025   BibTeX | EndNote: XML, Text | RIS

All known publications ...
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