W610
Core Facility Omics IT
Also known as:W610 Core Facility Omics IT; W610 Omics IT and Data Management
ID | I:(DE-He78)W610-20160331 |
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William, D.DKFZ* ; Bermúdez, M.DKFZ* ; Kübler, A.DKFZ* ; et al
17.6% of patients in a German cohort with exocrine pancreatic cancer were diagnosed with a genetic tumor syndrome—a case for universal genetic testing?
ESMO gastrointestinal oncology 9, 100218 (2025) [10.1016/j.esmogo.2025.100218]2025
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Zou, X. ; Nie, S. ; Cao, J. ; Shi, M. ; Schuck, K. ; Shi, Z. ; Zhang, L. ; Li, H. ; Sun, Y. ; Fang, C. ; Hu, J. ; Niu, Y. ; Yu, Y. ; Zhang, Z. ; Li, C. ; Hu, M. ; Wang, L. ; Jiang, K. ; Lu, Z. ; Akkan, J. ; Raulefs, S. ; Kahlert, C. ; Roth, S. ; Herr, I. ; Wan, Y. ; Mihaljevic, A. ; Qian, X. ; Zhang, Q. ; Wang, M. H. ; Kleeff, J. ; Friess, H. ; Gu, Z.DKFZ* ; Michalski, C. W. ; Shen, S. ; Kong, B.
ALDH1A3 promotes aggressive basal-like pancreatic cancer through an AP-1/RUNX2 enhancer network.
Oncogene nn, nn (2025) [10.1038/s41388-025-03530-w]2025
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Beumer, N. ; Imbusch, C. D. (First author)DKFZ* ; Kaufmann, T. ; Schmidleithner, L. ; Gütter, K. ; Stüve, P. ; Marchel, H. ; Weichenhan, D.DKFZ* ; Bähr, M.DKFZ* ; Ruhland, B. ; Marini, F. ; Sanderink, L. ; Ritter, U. ; Simon, M.DKFZ* ; Braband, K. L. ; Voss, M. M. ; Helbich, S. S. ; Mihoc, D. M. ; Hotz-Wagenblatt, A.DKFZ* ; Nassabi, H. ; Eigenberger, A. ; Prantl, L. ; Gebhard, C. ; Rehli, M. ; Strieder, N. ; Singh, K. ; Schmidl, C. ; Plass, C.DKFZ* ; Huehn, J. ; Hehlgans, T. ; Polansky, J. K. ; Brors, B. (Last author)DKFZ* ; Delacher, M. ; Feuerer, M.
DNA hypomethylation traits define human regulatory T cells in cutaneous tissue and identify their blood recirculating counterparts.
Nature immunology 26(8), 1315-1328 (2025) [10.1038/s41590-025-02210-x]2025
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Gehrs, S. (First author)DKFZ* ; Gu, Z. ; Hey, J.DKFZ* ; Weichenhan, D.DKFZ* ; Buckwalter, N.DKFZ* ; Jakab, M. V.DKFZ* ; Hotz-Wagenblatt, A.DKFZ* ; Breuer, K.DKFZ* ; Prada, M. L.DKFZ* ; Hübschmann, D.DKFZ* ; Schlereth, K.DKFZ* ; Plass, C. (Last author)DKFZ* ; Augustin, H. (Last author)DKFZ*
DNMT3A-dependent DNA methylation shapes the endothelial enhancer landscape.
Nucleic acids research 53(10), gkaf435 (2025) [10.1093/nar/gkaf435]2025
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Betz, A. ; Huang, H.-E. ; Gu, Z. ; Colasanti, O. ; Li, T.-F. ; Hesebeck-Brinckmann, J. ; Gillich, N.DKFZ* ; Gnouamozi, G. E. ; Schlesner, M.DKFZ* ; Vondran, F. W. R. ; Urban, S. ; Bartenschlager, R.DKFZ* ; Binder, M.DKFZ* ; Lohmann, V.
Reconstitution of interferon regulatory factor 7 expression restores interferon beta induction in Huh7 cells
Journal of virology 99(6), e0070325 (2025) [10.1128/jvi.00703-25]2025
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Li, T.-F. ; Rothhaar, P. ; Lang, A. ; Grünvogel, O. ; Colasanti, O. ; Ugarte, S. M. O. ; Traut, J. ; Piras, A. ; Acosta-Rivero, N. ; Gonçalves Magalhães, V.DKFZ* ; Springer, E. ; Betz, A. ; Huang, H.-E. ; Park, J.DKFZ* ; Qiu, R. ; Gnouamozi, G. E. ; Mehnert, A.-K. ; Thi, V. L. D. ; Urban, S. ; Muckenthaler, M. ; Schlesner, M.DKFZ* ; Wohlleber, D. ; Binder, M.DKFZ* ; Bartenschlager, R.DKFZ* ; Pichlmair, A. ; Lohmann, V.
RBM39 shapes innate immunity by controlling the expression of key factors of the interferon response.
Frontiers in immunology 16, 1568056 (2025) [10.3389/fimmu.2025.1568056]2025
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Volkmar, M. (First author)DKFZ* ; Hoser, D.Extern* ; Lauenstein, C.DKFZ* ; Rebmann, J. ; Hotz-Wagenblatt, A.DKFZ* ; Rieger, J. H.DKFZ* ; Poschke, I.DKFZ* ; Becker, J.DKFZ* ; Riemer, A. B.DKFZ* ; Sprick, M.DKFZ* ; Trumpp, A.DKFZ* ; Strobel, O. ; Blankenstein, T. ; Willimsky, G.DKFZ* ; Offringa, R. (Last author)DKFZ*
Enhanced mutanome analysis towards the induction of neoepitope-reactive T-cell responses for personalized immunotherapy of pancreatic cancer.
Journal for ImmunoTherapy of Cancer 13(6), e011802 (2025) [10.1136/jitc-2025-011802]2025
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Vlachavas, E.-I. (First author)DKFZ* ; Voutetakis, K. ; Kosmidou, V. ; Tsikalakis, S.DKFZ* ; Roditis, S. ; Pateas, K. ; Kim, R. ; Pagel, K. ; Wolf, S.DKFZ* ; Warsow, G.DKFZ* ; Dimitrakopoulou-Strauss, A.DKFZ* ; Zografos, G. N. ; Pintzas, A. ; Betge, J.DKFZ* ; Papadodima, O. ; Wiemann, S. (Last author)DKFZ*
Molecular and functional profiling unravels targetable vulnerabilities in colorectal cancer.
Molecular oncology 19(6), 1751-1774 (2025) [DOI:10.1002/1878-0261.13814]2025
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Pfaff, E. (First author)DKFZ* ; Schramm, K.DKFZ* ; Blattner-Johnson, M.DKFZ* ; Jones, B. C.DKFZ* ; Stark, S.DKFZ* ; Balasubramanian, G. P.DKFZ* ; Previti, C.DKFZ* ; Autry, R. J.DKFZ* ; Fiesel, P.DKFZ* ; Sahm, F.DKFZ* ; Reuss, D.DKFZ* ; von Deimling, A.DKFZ* ; van Tilburg, C. M.DKFZ* ; Pajtler, K. W.DKFZ* ; Milde, T.DKFZ* ; Dirksen, U. ; Kramm, C. M. ; von Bueren, A. O. ; Munthe-Kaas, M. C. ; Øra, I. ; Pfister, S. M.DKFZ* ; Witt, O.DKFZ* ; Jones, D. (Last author)DKFZ*
Pediatric spinal high-grade glioma in the pediatric precision oncology registry INFORM: identification of potential therapeutic targets
Neuro-oncology advances 7(1), vdae185 (2025) [10.1093/noajnl/vdae185]2025
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Salcedo, A. ; Tarabichi, M. ; Buchanan, A. ; et al
Crowd-sourced benchmarking of single-sample tumor subclonal reconstruction
Nature biotechnology 43, 581–592 (2025) [10.1038/s41587-024-02250-y]2025
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