W610
Core Facility Omics IT
Also known as:W610 Core Facility Omics IT; W610 Omics IT and Data Management
| ID | I:(DE-He78)W610-20160331 |
Recent Publications
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Journal Article
Lin, Y.-Y. (First author)DKFZ* ; Breuer, K.DKFZ* ; Weichenhan, D.DKFZ* ; Lafrenz, P.DKFZ* ; Sarnataro, A. ; Wilk, A.DKFZ* ; Chepeleva, M. ; Mücke, O.DKFZ* ; Schönung, M.DKFZ* ; Petermann, F.DKFZ* ; Kensche, P. R.DKFZ* ; Weiser, L.DKFZ* ; Thommen, F.DKFZ* ; Giacomelli, G. ; Nordstroem, K. ; Gonzalez-Avalos, E. ; Merkel, A. ; Kretzmer, H. ; Fischer, J. ; Krämer, S.DKFZ* ; Iskar, M.DKFZ* ; Wolf, S.DKFZ* ; Buchhalter, I.DKFZ* ; Esteller, M. ; Lawerenz, C. ; Twardziok, S. ; Zapatka, M.DKFZ* ; Hovestadt, V. ; Schlesner, M. ; Schulz, M. H. ; Hoffmann, S. ; Gerhäuser, C.DKFZ* ; Walter, J. ; Hartmann, M.DKFZ* ; Lipka, D.DKFZ* ; Assenov, Y. ; Bock, C. ; Plass, C.DKFZ* ; Toth, R. (Last author)DKFZ* ; Lutsik, P. (Last author)DKFZ*
Pipeline Olympics: continuable benchmarking of computational workflows for DNA methylation sequencing data against an experimental gold standard.
Nucleic acids research 53(19), gkaf970 (2025) [10.1093/nar/gkaf970]2025
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Pfaff, E. (First author)DKFZ* ; Schramm, K.DKFZ* ; Blattner-Johnson, M.DKFZ* ; Jones, B. C.DKFZ* ; Stark, S.DKFZ* ; Balasubramanian, G. P.DKFZ* ; Previti, C.DKFZ* ; Autry, R. J.DKFZ* ; Fiesel, P.DKFZ* ; Sahm, F.DKFZ* ; Reuss, D.DKFZ* ; von Deimling, A.DKFZ* ; van Tilburg, C. M.DKFZ* ; Pajtler, K. W.DKFZ* ; Milde, T.DKFZ* ; Dirksen, U.DKFZ* ; Kramm, C. M. ; von Bueren, A. O. ; Hutter, C. ; de Wilde, B. ; Molenaar, J. ; Gerber, N. U. ; Lohi, O. ; Munthe-Kaas, M. C. ; Georgantzi, K. ; Kazanowska, B. ; Zápotocký, M. ; Kattamis, A. ; Filippidou, M. ; Fried, I. ; Pfister, S. M.DKFZ* ; Witt, O.DKFZ* ; Jones, D. (Last author)DKFZ*
Molecular characterization and clinical features of diffuse midline glioma in the pediatric precision oncology registry INFORM.
Acta neuropathologica 150(1), 42 (2025) [10.1007/s00401-025-02945-9]2025
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Journal Article
William, D.DKFZ* ; Bermúdez, M.DKFZ* ; Kübler, A.DKFZ* ; et al
17.6% of patients in a German cohort with exocrine pancreatic cancer were diagnosed with a genetic tumor syndrome—a case for universal genetic testing?
ESMO gastrointestinal oncology 9, 100218 (2025) [10.1016/j.esmogo.2025.100218]2025
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Beumer, N. ; Imbusch, C. D. (First author)DKFZ* ; Kaufmann, T. ; Schmidleithner, L. ; Gütter, K. ; Stüve, P. ; Marchel, H. ; Weichenhan, D.DKFZ* ; Bähr, M.DKFZ* ; Ruhland, B. ; Marini, F. ; Sanderink, L. ; Ritter, U. ; Simon, M.DKFZ* ; Braband, K. L. ; Voss, M. M. ; Helbich, S. S. ; Mihoc, D. M. ; Hotz-Wagenblatt, A.DKFZ* ; Nassabi, H. ; Eigenberger, A. ; Prantl, L. ; Gebhard, C. ; Rehli, M. ; Strieder, N. ; Singh, K. ; Schmidl, C. ; Plass, C.DKFZ* ; Huehn, J. ; Hehlgans, T. ; Polansky, J. K. ; Brors, B. (Last author)DKFZ* ; Delacher, M. ; Feuerer, M.
DNA hypomethylation traits define human regulatory T cells in cutaneous tissue and identify their blood recirculating counterparts.
Nature immunology 26(8), 1315-1328 (2025) [10.1038/s41590-025-02210-x]2025
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Journal Article
Gehrs, S. (First author)DKFZ* ; Gu, Z. ; Hey, J.DKFZ* ; Weichenhan, D.DKFZ* ; Buckwalter, N.DKFZ* ; Jakab, M. V.DKFZ* ; Hotz-Wagenblatt, A.DKFZ* ; Breuer, K.DKFZ* ; Prada, M. L.DKFZ* ; Hübschmann, D.DKFZ* ; Schlereth, K.DKFZ* ; Plass, C. (Last author)DKFZ* ; Augustin, H. (Last author)DKFZ*
DNMT3A-dependent DNA methylation shapes the endothelial enhancer landscape.
Nucleic acids research 53(10), gkaf435 (2025) [10.1093/nar/gkaf435]2025
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Journal Article
Betz, A. ; Huang, H.-E. ; Gu, Z. ; Colasanti, O. ; Li, T.-F. ; Hesebeck-Brinckmann, J. ; Gillich, N.DKFZ* ; Gnouamozi, G. E. ; Schlesner, M.DKFZ* ; Vondran, F. W. R. ; Urban, S. ; Bartenschlager, R.DKFZ* ; Binder, M.DKFZ* ; Lohmann, V.
Reconstitution of interferon regulatory factor 7 expression restores interferon beta induction in Huh7 cells
Journal of virology 99(6), e0070325 (2025) [10.1128/jvi.00703-25]2025
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Journal Article
Li, T.-F. ; Rothhaar, P. ; Lang, A. ; Grünvogel, O. ; Colasanti, O. ; Ugarte, S. M. O. ; Traut, J. ; Piras, A. ; Acosta-Rivero, N. ; Gonçalves Magalhães, V.DKFZ* ; Springer, E. ; Betz, A. ; Huang, H.-E. ; Park, J.DKFZ* ; Qiu, R. ; Gnouamozi, G. E. ; Mehnert, A.-K. ; Thi, V. L. D. ; Urban, S. ; Muckenthaler, M. ; Schlesner, M.DKFZ* ; Wohlleber, D. ; Binder, M.DKFZ* ; Bartenschlager, R.DKFZ* ; Pichlmair, A. ; Lohmann, V.
RBM39 shapes innate immunity by controlling the expression of key factors of the interferon response.
Frontiers in immunology 16, 1568056 (2025) [10.3389/fimmu.2025.1568056]2025
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Journal Article (Review Article)
Hartmann, M. (First author)DKFZ* ; Schönung, M. (First author)DKFZ* ; Rajak, J. ; Maurer, V.DKFZ* ; Hai, L.DKFZ* ; Bauer, K.DKFZ* ; Hakobyan, M.DKFZ* ; Stäble, S.DKFZ* ; Langstein, J.DKFZ* ; Jardine, L. ; Roelz, R. ; Bohler, S. ; Khabirova, E. ; Maag, A.-H. ; Vonficht, D.DKFZ* ; Lebrecht, D. ; Bernt, K. M. ; Tan, K. ; Chen, C. ; Alikarami, F. ; Meyer, J. ; Wang, J. ; Boch, T. ; Flore, N. V.DKFZ* ; Lutsik, P.DKFZ* ; Milsom, M.DKFZ* ; Raffel, S. ; Buske, C. ; Haas, S. ; Haniffa, M. ; Mallm, J.-P.DKFZ* ; Behjati, S. ; Bonder, M. J.DKFZ* ; Fröhling, S.DKFZ* ; Stieglitz, E. ; Niemeyer, C. M. ; Hey, J. (Last author)DKFZ* ; Flotho, C.DKFZ* ; Plass, C. (Last author)DKFZ* ; Erlacher, M.DKFZ* ; Schlesner, M. (Last author)DKFZ* ; Lipka, D. (Last author)DKFZ*
Molecular Plasticity Results in Oncofetal Reprogramming and Therapeutic Vulnerabilities in Juvenile Myelomonocytic Leukemia.
Blood cancer discovery nn, nn (2025) [10.1158/2643-3230.BCD-25-0246]2025
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Preprint
Sill, M. (First author)DKFZ* ; Schrimpf, D.DKFZ* ; Patel, A.DKFZ* ; et al
Advancing CNS tumor diagnostics with expanded DNA methylation-based classification
[10.1101/2025.05.28.25328344]
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Journal Article
Till, A. ; Siddiqui, R. A. ; Altbürger, C. ; Schwarz, R. ; Huebner, T. ; Wolf, J. ; Andres, D. ; Anker, A. ; Aretz, S. ; Haack, T. B. ; Berlage, T. ; Beule, D. ; Boerries, M. ; Buchhalter, I.DKFZ* ; Bussmann, J. ; Engel, C. ; Friedrichs, J. ; Fröhling, S.DKFZ* ; Haenisch, B. ; Hahne, A. ; Hübschmann, D.DKFZ* ; von Kessel, F. ; Klatt, R. ; Kreutzfeldt, S.DKFZ* ; Kron, A. ; Krude, H. ; Lübbe, A. ; Lührig, U. ; Malek, N. ; Mertes, C. ; Möller, Y. ; Mundlos, C. ; Nöthen, M. M. ; Ossowski, S. ; Pötschke, L. ; Rasokat, A. ; Riess, O. ; Schade, S. ; Schirmacher, P. ; Schmutzler, R. ; Scholl, C. ; Semler, S. C. ; Spielmann, M. ; Stegle, O.DKFZ* ; Stenzinger, A. ; Straßburger, J. ; Schröck, E. ; Krawczak, M. ; Kohlbacher, O.
Germany's national genomDE strategy.
Nature medicine 31, 3981–3984 (2025) [10.1038/s41591-025-03991-2]2025
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All known publications ...
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