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B420
Genominstabilität in Tumoren| ID | I:(DE-He78)B420-20160331 |
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Journal Article
Multiomic profiling links L1 retrotransposition to genomic instability and ecDNA in bladder cancer.
Nature Communications 17(1), 6384 (2026) [10.1038/s41467-026-75399-6]
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Journal Article
Preclinical drug screen identifies WEE1 inhibitor and vinca alkaloid as a combination treatment concept for Li-Fraumeni syndrome medulloblastoma.
iScience 29(2), 114564 (2026) [10.1016/j.isci.2025.114564]
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Journal Article
Enhancer hijacking discovery in acute myeloid leukemia by pyjacker identifies MNX1 activation via deletion 7q.
Blood cancer discovery 6(4), 343-363 (2025) [10.1158/2643-3230.BCD-24-0278]
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Dissertation / PhD Thesis
Investigating the mechanistic basis of chromothripsis initiation and the clonal evolution of chromothriptic cells
Dissertation, University of Heidelberg, 2025
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Dissertation / PhD Thesis
Investigating Treatment Resistance in SonicHedgehog-Medulloblastoma in Patients with LiFraumeni Syndrome
Dissertation, University of Heidelberg, 2025
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Journal Article (Erratum/Correction)
Author Correction: Multi-omic and single-cell profiling of chromothriptic medulloblastoma reveals genomic and transcriptomic consequences of genome instability.
Nature Communications 16(1), 1085 (2025) [10.1038/s41467-025-56164-7]
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Journal Article (Review Article)
Chromothripsis in cancer.
Nature reviews / Cancer 25(2), 79–92 (2025) [10.1038/s41568-024-00769-5]
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Journal Article
HIPSD&R-seq enables scalable genomic copy number and transcriptome profiling.
Genome biology 25(1), 316 (2024) [10.1186/s13059-024-03450-0]
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Journal Article (Review Article)
Cancer Hallmarks: Piecing the Puzzle Together
Cancer discovery 14(4), 674 - 682 (2024) [10.1158/2159-8290.CD-24-0097]
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Journal Article
Spatio-temporal transcriptomics of chromothriptic SHH-medulloblastoma identifies multiple genetic clones that resist treatment and drive relapse.
Nature Communications 15(1), 10370 (2024) [10.1038/s41467-024-54709-w]
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All known publications ...
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