B420

Genominstabilität in Tumoren
IDI:(DE-He78)B420-20160331

Recent Publications

All known publications ...
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Preclinical drug screen identifies WEE1 inhibitor and vinca alkaloid as a combination treatment concept for Li-Fraumeni syndrome medulloblastoma.
iScience 29(2), 114564 () [10.1016/j.isci.2025.114564]  GO DBCoverage   Download fulltextFulltext by Pubmed Central BibTeX | EndNote: XML, Text | RIS

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Enhancer hijacking discovery in acute myeloid leukemia by pyjacker identifies MNX1 activation via deletion 7q.
Blood cancer discovery 6(4), 343-363 () [10.1158/2643-3230.BCD-24-0278]  GO BibTeX | EndNote: XML, Text | RIS

http://join2-wiki.gsi.de/foswiki/pub/Main/Artwork/join2_logo100x88.png Dissertation / PhD Thesis
Investigating the mechanistic basis of chromothripsis initiation and the clonal evolution of chromothriptic cells
Dissertation, University of Heidelberg, 2025  GO BibTeX | EndNote: XML, Text | RIS

http://join2-wiki.gsi.de/foswiki/pub/Main/Artwork/join2_logo100x88.png Dissertation / PhD Thesis
Investigating Treatment Resistance in SonicHedgehog-Medulloblastoma in Patients with LiFraumeni Syndrome
Dissertation, University of Heidelberg, 2025  GO BibTeX | EndNote: XML, Text | RIS

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Author Correction: Multi-omic and single-cell profiling of chromothriptic medulloblastoma reveals genomic and transcriptomic consequences of genome instability.
Nature Communications 16(1), 1085 () [10.1038/s41467-025-56164-7]  GO DBCoverage   Download fulltextFulltext by Pubmed Central BibTeX | EndNote: XML, Text | RIS

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Chromothripsis in cancer.
Nature reviews / Cancer 25(2), 79–92 () [10.1038/s41568-024-00769-5]  GO  Download fulltext Files BibTeX | EndNote: XML, Text | RIS

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HIPSD&R-seq enables scalable genomic copy number and transcriptome profiling.
Genome biology 25(1), 316 () [10.1186/s13059-024-03450-0]  GO OpenAccess  Download fulltext Files  Download fulltextFulltext by Pubmed Central BibTeX | EndNote: XML, Text | RIS

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Cancer Hallmarks: Piecing the Puzzle Together
Cancer discovery 14(4), 674 - 682 () [10.1158/2159-8290.CD-24-0097]  GO  Download fulltext Files  Download fulltextFulltext BibTeX | EndNote: XML, Text | RIS

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Spatio-temporal transcriptomics of chromothriptic SHH-medulloblastoma identifies multiple genetic clones that resist treatment and drive relapse.
Nature Communications 15(1), 10370 () [10.1038/s41467-024-54709-w]  GO OpenAccess  Download fulltext Files  Download fulltextFulltext by Pubmed Central BibTeX | EndNote: XML, Text | RIS

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Multi-omic and single-cell profiling of chromothriptic medulloblastoma reveals genomic and transcriptomic consequences of genome instability.
Nature Communications 15(1), 10183 () [10.1038/s41467-024-54547-w]  GO OpenAccess  Download fulltext Files BibTeX | EndNote: XML, Text | RIS

All known publications ...
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 Record created 2019-12-05, last modified 2022-03-18



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