Journal Article DKFZ-2022-00660

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Semantic segmentation of multispectral photoacoustic images using deep learning.

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2022
Elsevier Amsterdam ˜[u.a.]œ

Photoacoustics 26, 100341 () [10.1016/j.pacs.2022.100341]
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Abstract: Photoacoustic (PA) imaging has the potential to revolutionize functional medical imaging in healthcare due to the valuable information on tissue physiology contained in multispectral photoacoustic measurements. Clinical translation of the technology requires conversion of the high-dimensional acquired data into clinically relevant and interpretable information. In this work, we present a deep learning-based approach to semantic segmentation of multispectral photoacoustic images to facilitate image interpretability. Manually annotated photoacoustic and ultrasound imaging data are used as reference and enable the training of a deep learning-based segmentation algorithm in a supervised manner. Based on a validation study with experimentally acquired data from 16 healthy human volunteers, we show that automatic tissue segmentation can be used to create powerful analyses and visualizations of multispectral photoacoustic images. Due to the intuitive representation of high-dimensional information, such a preprocessing algorithm could be a valuable means to facilitate the clinical translation of photoacoustic imaging.

Keyword(s): Deep learning ; Medical image segmentation ; Multispectral imaging ; Optoacoustics ; Photoacoustics

Classification:

Note: #EA:E130#LA:E130#

Contributing Institute(s):
  1. E130 Intelligente Medizinische Systeme (E130)
  2. E230 Medizinische Bildverarbeitung (E230)
  3. C060 Biostatistik (C060)
Research Program(s):
  1. 315 - Bildgebung und Radioonkologie (POF4-315) (POF4-315)

Appears in the scientific report 2022
Database coverage:
Medline ; Creative Commons Attribution-NonCommercial-NoDerivs CC BY-NC-ND (No Version) ; DOAJ ; Article Processing Charges ; Clarivate Analytics Master Journal List ; Current Contents - Engineering, Computing and Technology ; Current Contents - Life Sciences ; DOAJ Seal ; Essential Science Indicators ; Fees ; IF >= 5 ; JCR ; SCOPUS ; Science Citation Index Expanded ; Web of Science Core Collection
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 Record created 2022-04-06, last modified 2024-02-29


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