D192
T-Zell-Metabolismus
ID | I:(DE-He78)D192-20160331 |
Recent Publications
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Journal Article
Hering, M. (First author)DKFZ* ; Madi, A. A. M.DKFZ* ; Sandhoff, R.DKFZ* ; Ma, S.DKFZ* ; Wu, J.DKFZ* ; Mieg, A.DKFZ* ; Richter, K.DKFZ* ; Mohr, K.DKFZ* ; Knabe, N.DKFZ* ; Stichling, D.DKFZ* ; Poschet, G. ; Bestvater, F.DKFZ* ; Frank, L. J.DKFZ* ; Utikal, J.DKFZ* ; Umansky, V.DKFZ* ; Cui, G. (Last author)DKFZ*
Sphinganine recruits TLR4 adaptors in macrophages and promotes inflammation in murine models of sepsis and melanoma.
Nature Communications 15(1), 6067 (2024) [10.1038/s41467-024-50341-w]2024
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Journal Article
Wißfeld, J. (First author)DKFZ* ; Hering, M.DKFZ* ; ten Bosch, N.DKFZ* ; Cui, G. (Last author)DKFZ*
The immunosuppressive drug cyclosporin A has an immunostimulatory function in CD8+ T cells.
European journal of immunology 54(7), e2350825 (2024) [10.1002/eji.202350825]2024
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Ma, S. ; Sandhoff, R. (First author)DKFZ* ; Luo, X. ; Shang, F.DKFZ* ; Shi, Q. ; Li, Z. ; Wu, J. ; Ming, Y. ; Schwarz, F.DKFZ* ; Madi, A. A. M.DKFZ* ; Weisshaar, N.DKFZ* ; Mieg, A.DKFZ* ; Hering, M.DKFZ* ; Zettl, F.DKFZ* ; Yan, X.DKFZ* ; Mohr, K.DKFZ* ; ten Bosch, N.DKFZ* ; Li, Z.DKFZ* ; Poschet, G. ; Rodewald, H.-R.DKFZ* ; Papavasiliou, N.DKFZ* ; Wang, X. ; Gao, P. ; Cui, G. (Last author)DKFZ*
Serine enrichment in tumors promotes regulatory T cell accumulation through sphinganine-mediated regulation of c-Fos.
Science immunology 9(94), eadg8817 (2024) [10.1126/sciimmunol.adg8817]2024
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Journal Article
Madi, A. A. M. (First author)DKFZ* ; Wu, J.DKFZ* ; Ma, S.DKFZ* ; Weisshaar, N.DKFZ* ; Mieg, A.DKFZ* ; Hering, M.DKFZ* ; Ming, Y.DKFZ* ; Zettl, F.DKFZ* ; Mohr, K.DKFZ* ; Ten Bosch, N.DKFZ* ; Schlimbach, T.DKFZ* ; Hertel, F.DKFZ* ; Cui, G. (Last author)DKFZ*
Regulatory T cell-derived interleukin-15 promotes the diversity of immunological memory.
European journal of immunology 53(1), e2149400 (2023) [10.1002/eji.202149400]2023
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Miao, B. (First author)DKFZ* ; Hu, Z. (First author)DKFZ* ; Mezzadra, R. ; Hoeijmakers, L. ; Fauster, A. ; Du, S.DKFZ* ; Yang, Z. ; Sator-Schmitt, M.DKFZ* ; Engel, H.DKFZ* ; Li, X. ; Broderick, C. ; Jin, G. ; Gomez-Eerland, R. ; Rozeman, L. ; Lei, X. ; Matsuo, H.DKFZ* ; Yang, C.DKFZ* ; Hofland, I. ; Peters, D. ; Broeks, A. ; Laport, E.DKFZ* ; Fitz, A.DKFZ* ; Zhao, X.DKFZ* ; Mahmoud, M. A. A.DKFZ* ; Ma, X.DKFZ* ; Sander, S.DKFZ* ; Liu, H.-K.DKFZ* ; Cui, G.DKFZ* ; Gan, Y. ; Wu, W. ; Xiao, Y. ; Heck, A. J. R. ; Guan, W. ; Lowe, S. W. ; Horlings, H. M. ; Wang, C. ; Brummelkamp, T. R. ; Blank, C. U. ; Schumacher, T. N. M. ; Sun, C. (Last author)DKFZ*
CMTM6 shapes antitumor T cell response through modulating protein expression of CD58 and PD-L1.
Cancer cell 41(10), 1817 - 1828.e9 (2023) [10.1016/j.ccell.2023.08.008]2023
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Journal Article
Weisshaar, N. (First author)DKFZ* ; Ma, S. ; Ming, Y. ; Madi, A. A. M.DKFZ* ; Mieg, A.DKFZ* ; Hering, M.DKFZ* ; Zettl, F.DKFZ* ; Mohr, K.DKFZ* ; ten Bosch, N.DKFZ* ; Stichling, D.DKFZ* ; Buettner, M. ; Poschet, G. ; Klinke, G. ; Schulz, M. ; Kunze-Rohrbach, N. ; Kerber, C. ; Klein, I. M. ; Wu, J. ; Wang, X. ; Cui, G. (Last author)DKFZ*
The malate shuttle detoxifies ammonia in exhausted T cells by producing 2-ketoglutarate.
Nature immunology 24(11), 1921-1932 (2023) [10.1038/s41590-023-01636-5]2023
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Betz, U. A. K. ; Arora, L. ; Assal, R. A. ; Azevedo, H. ; Baldwin, J. ; Becker, M. S. ; Bostock, S. ; Cheng, V. ; Egle, T. ; Ferrari, N. ; Schneider-Futschik, E. K. ; Gerhardy, S. ; Hammes, A. ; Harzheim, A. ; Herget, T. ; Jauset, C. ; Kretschmer, S. ; Lammie, C. ; Kloss, N. ; Fernandes, S. M. ; Mitrofan, C.-G. ; Myrgorodska, I. ; Nedbalek, D. ; Neumann, S. G. ; Paffenholz, S. ; Ponce, L. P. ; Rogell, B. ; Savic, D. ; Velikova, G. ; Schumacher, C. ; Weisshaar, N.DKFZ* ; Yahya, M. ; Yang, J. Y. C. ; Zhao, G.
Game changers in science and technology - now and beyond
Technological forecasting and social change 193, 122588 (2023) [10.1016/j.techfore.2023.122588]2023
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Journal Article (Review Article)
Wißfeld, J. (First author)DKFZ* ; Werner, A. (First author)DKFZ* ; Yan, X. (First author)DKFZ* ; Ten Bosch, N. (First author)DKFZ* ; Cui, G. (Last author)DKFZ*
Metabolic regulation of immune responses to cancer.
Cancer biology & medicine 29(11), 1528-1542 (2022) [10.20892/j.issn.2095-3941.2022.0381]2022
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Journal Article
Madi, A. A. M. (First author)DKFZ* ; Weisshaar, N.DKFZ* ; Buettner, M. ; Poschet, G. ; Ma, S.DKFZ* ; Wu, J.DKFZ* ; Mieg, A.DKFZ* ; Hering, M.DKFZ* ; Ming, Y.DKFZ* ; Mohr, K.DKFZ* ; Bosch, N.DKFZ* ; Cui, G. (Last author)DKFZ*
CD8 agonism functionally activates memory T cells and enhances antitumor immunity
International journal of cancer 151(5), 797-808 (2022) [10.1002/ijc.34059]2022
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Journal Article
Weisshaar, N. (First author)DKFZ* ; Wu, J.DKFZ* ; Ming, Y.DKFZ* ; Madi, A. A. M.DKFZ* ; Hotz-Wagenblatt, A.DKFZ* ; Ma, S.DKFZ* ; Mieg, A.DKFZ* ; Hering, M.DKFZ* ; Zettl, F.DKFZ* ; Mohr, K.DKFZ* ; Schlimbach, T.DKFZ* ; Ten Bosch, N.DKFZ* ; Hertel, F.DKFZ* ; Müller, L.DKFZ* ; Byren, H.DKFZ* ; Wang, M.DKFZ* ; Borgers, H.DKFZ* ; Munz, M.DKFZ* ; Schmitt, L.DKFZ* ; van der Hoeven, F.DKFZ* ; Kloz, U.DKFZ* ; Carretero, R.DKFZ* ; Schleußner, N.DKFZ* ; Jackstadt, R.-F.DKFZ* ; Hofmann, I.DKFZ* ; Cui, G. (Last author)DKFZ*
Rgs16 promotes antitumor CD8+ T cell exhaustion.
Science immunology 7(71), eabh1873 (2022) [10.1126/sciimmunol.abh1873]2022
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